Description

Phloretin-3-Hydroxy-2-o-Glucoside is a specific dihydrochalcone glucoside, a natural polyphenolic compound derived from apple tree bark and leaves. This compound matters for its role as a key intermediate in the biosynthesis of phloridzin and for its intrinsic biological activity, which is of significant interest in research and development. Industries involved in nutraceutical ingredient manufacturing, cosmetic active development, and pharmaceutical research require this high-purity standard for their formulation and investigative work.

Application

• Pharmaceutical Research: Used as a reference standard and active pharmaceutical ingredient (API) intermediate in metabolic and diabetes-related studies.
• Nutraceutical Formulations: Incorporated into dietary supplements targeting blood sugar management and antioxidant support.
• Cosmetic Actives: Serves as a skin-brightening and anti-aging agent in serums and creams due to its tyrosinase inhibition properties.
• Biochemical Research: Employed in enzymatic studies, particularly those involving glycosyltransferases and metabolic pathways like flavonoid biosynthesis.
• Food Science: Studied as a natural sweetener modulator and functional food additive.
• Analytical Chemistry: Utilized as a high-purity calibration standard for HPLC and LC-MS analysis in quality control laboratories.

Basic Information

Product Name	Phloretin-3-Hydroxy-2-o-Glucoside
CAS No.	30779-02-3
Molecular Formula	C21H24O11
Molecular Weight	452.41 g/mol
Synonyms	Phloretin 3'-O-glucoside; 3-Hydroxyphloretin 2'-O-β-D-glucopyranoside; Phloretin 3'-O-β-D-glucopyranoside; 2',4,4',6'-Tetrahydroxydihydrochalcone 3'-O-β-D-glucoside; Dihydrochalcone glucoside; Trilobatin; Contact for additional synonyms
EINECS	Contact for details

Quality Control

Our Phloretin-3-Hydroxy-2-o-Glucoside is produced and tested under a strict quality management system. Each batch undergoes comprehensive analytical testing including HPLC for purity, IR and NMR for structural confirmation, and residual solvent analysis to ensure it meets the high standards required for research and commercial use. Certificates of Analysis (COA) documenting all test results are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is light-sensitive and should be handled under appropriate conditions to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 95.0%
Water Content	≤ 5.0% (KF)
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm
Residual Solvents	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.