Description

(1R,4S)-6-[(2-Methoxyphenyl)Methoxycarbonyl]-7-Oxabicyclo[2.2.1]Heptan E-5-Carboxylic Acid is a high-purity, chiral bicyclic compound that serves as a critical advanced pharmaceutical intermediate. Its unique stereochemistry and functional groups make it an essential building block for the synthesis of complex, biologically active molecules. This product is primarily targeted at research institutions and pharmaceutical manufacturers engaged in the development of novel therapeutic agents, particularly in areas requiring precise stereochemical control.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new active pharmaceutical ingredients (APIs), especially for central nervous system (CNS) and anti-inflammatory drugs.
• Asymmetric Synthesis: Utilized in stereoselective synthesis to construct complex molecular architectures with high enantiomeric purity.
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Process Chemistry Development: Used in scaling up synthetic routes from laboratory to pilot plant and commercial manufacturing scales.
• Reference Standard: Employed as an analytical standard for quality control and method validation in pharmaceutical analysis.

Basic Information

Product Name	(1R,4S)-6-[(2-Methoxyphenyl)Methoxycarbonyl]-7-Oxabicyclo[2.2.1]Heptan E-5-Carboxylic Acid
CAS No.	30627-47-5
Molecular Formula	C16H18O6
Molecular Weight	306.31 g/mol
Synonyms	6-[(2-Methoxyphenoxy)carbonyl]-7-oxabicyclo[2.2.1]hept-5-ene-2-carboxylic acid, (1R,4S)-rel-; 7-Oxabicyclo[2.2.1]hept-5-ene-2-carboxylic acid, 6-[[(2-methoxyphenyl)methoxy]carbonyl]-, (1R,4S)-; (1R,4S)-6-[(2-Methoxyphenoxy)carbonyl]-7-oxabicyclo[2.2.1]hept-5-ene-2-carboxylic acid; Bicyclic lactone acid derivative; Chiral oxabicycloheptane carboxylic acid.
EINECS	Contact for details

Quality Control

Our production of (1R,4S)-6-[(2-Methoxyphenyl)Methoxycarbonyl]-7-Oxabicyclo[2.2.1]Heptan E-5-Carboxylic Acid adheres to stringent quality management systems. Every batch undergoes comprehensive analytical testing, including chiral purity analysis by HPLC, to ensure it meets the exacting standards required for pharmaceutical R&D and manufacturing. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with each shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.