Description

1-Chloro-3-tert-Butyl-Benzene is a versatile chlorinated aromatic intermediate of significant importance in advanced organic synthesis. Its unique structure, featuring both a chloro and a bulky tert-butyl substituent, makes it a valuable building block for creating complex molecules with tailored properties. This compound is primarily sought after by R&D chemists and process engineers in the pharmaceutical, agrochemical, and specialty chemical industries for applications ranging from ligand synthesis to material science.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds requiring sterically hindered aromatic systems.
• Agrochemical Synthesis: Used in the development of herbicides, fungicides, and insecticides where the tert-butyl group can influence biological activity and environmental stability.
• Ligand and Catalyst Preparation: Acts as a starting material for synthesizing specialized ligands used in transition metal catalysis, such as palladium-catalyzed cross-coupling reactions.
• Material Science Research: Employed in the creation of monomers or additives for advanced polymers, liquid crystals, or organic electronic materials.
• Organic Synthesis Building Block: Utilized in Friedel-Crafts alkylation/acylation reactions and nucleophilic aromatic substitution, leveraging the directing effects of its substituents.
• Fine Chemical Production: Integral to the manufacture of dyes, pigments, and other performance chemicals requiring specific aromatic architectures.

Basic Information

Product Name	1-Chloro-3-tert-Butyl-Benzene
CAS No.	3972-55-2
Molecular Formula	C10H13Cl
Molecular Weight	168.66 g/mol
Synonyms	3-tert-Butylchlorobenzene; 1-Chloro-3-(1,1-dimethylethyl)benzene; 3-(tert-Butyl)chlorobenzene; m-tert-Butylchlorobenzene; 3-tert-Butyl-1-chlorobenzene; 3-(1,1-Dimethylethyl)chlorobenzene; Chloro-3-tert-butylbenzene
EINECS	223-600-0

Quality Control

Our 1-Chloro-3-tert-Butyl-Benzene is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including GC, HPLC, and NMR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, assay, and impurity profiles is provided with each shipment, ensuring full traceability and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials such as strong acids and bases. Recommended storage temperature is between 15°C and 25°C. Keep container tightly sealed when not in use to prevent moisture absorption and volatilization.

Specification

Item	Specification
Appearance	Clear, colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 98.0%
Water Content (KF)	≤ 0.1%
Related Substances (GC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.