Description

1,1-Dichloro-1-Fluoroacetone is a halogenated ketone building block of significant interest in advanced organic synthesis. Its unique structure, featuring both chlorine and fluorine atoms on the same carbon, makes it a versatile precursor for introducing functional complexity into target molecules. This compound is particularly valuable for researchers and process chemists in the pharmaceutical and agrochemical industries seeking to develop novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Serves as a key synthon for the preparation of fluorinated and chlorinated heterocycles and active pharmaceutical ingredients (APIs).
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides where the difluorochloromethyl group can enhance biological activity and metabolic stability.
• Fluorinated Building Block: A critical starting material for synthesizing more complex fluoroorganic compounds in material science and specialty chemistry.
• Chemical Research & Development: Employed in academic and industrial R&D for exploring new reaction pathways and creating libraries of fluorinated compounds for screening.
• Ligand and Catalyst Preparation: Can be utilized to synthesize specialized ligands or catalyst components for asymmetric synthesis and polymerization processes.

Basic Information

Product Name	1,1-Dichloro-1-Fluoroacetone
CAS No.	3929-28-0
Molecular Formula	C3H3Cl2FO
Molecular Weight	144.96 g/mol
Synonyms	1,1-Dichloro-1-fluoro-2-propanone; 1,1-Dichloro-1-fluoropropan-2-one; 1-Fluoro-1,1-dichloroacetone; Dichlorofluoroacetone; Acetone, 1,1-dichloro-1-fluoro-; 2-Propanone, 1,1-dichloro-1-fluoro-; 3929-28-0 (CAS)
EINECS	223-512-9

Quality Control

Every batch of 1,1-Dichloro-1-Fluoroacetone is produced and analyzed under strict quality management protocols. We ensure high purity and consistency to meet the rigorous demands of synthetic applications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to guarantee supply reliability and technical compliance for your critical processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials such as strong bases and reducing agents. Recommended storage temperature is 2-8°C to maintain stability. Keep container tightly sealed when not in use to prevent moisture absorption and volatility.

Specification

Item	Specification
Appearance	Clear, colorless to pale yellow liquid
Identification (IR)	Conforms to reference spectrum
Purity (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Density (at 20°C)	~1.50 g/mL

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.