Description

Acetone-2-13C CAS NO 3881-06-9 is a stable isotope-labeled analog of acetone, where the carbon atom at the 2-position is the carbon-13 (13C) isotope. This labeled compound is essential as an internal standard and tracer in quantitative analytical techniques, enabling precise measurement and metabolic pathway elucidation. It is a critical reagent for researchers and quality control laboratories in the pharmaceutical, environmental analysis, and life science sectors requiring high-fidelity isotopic purity.

Application

• Quantitative Analytical Internal Standard: Used in Gas Chromatography-Mass Spectrometry (GC-MS) and Liquid Chromatography-Mass Spectrometry (LC-MS) for the accurate quantification of acetone and related metabolites in complex biological or environmental matrices.
• Metabolic Pathway Tracing: Employed in 13C-NMR spectroscopy and isotope-ratio mass spectrometry studies to investigate metabolic fluxes, drug metabolism, and biochemical reaction mechanisms.
• Pharmaceutical Research & Development: Serves as a key labeled precursor or standard in the synthesis and analysis of isotopically labeled active pharmaceutical ingredients (APIs) and during pharmacokinetic studies.
• Environmental and Forensic Analysis: Acts as a tracer for studying atmospheric chemistry, solvent degradation pathways, and in forensic applications to determine the origin of materials.
• Clinical Diagnostics: Utilized in developing and validating diagnostic assays for conditions like diabetic ketoacidosis, where acetone is a key biomarker.
• Chemical Synthesis Research: Used as a labeled building block in organic synthesis to create more complex 13C-labeled compounds for mechanistic studies.

Basic Information

Product Name	Acetone-2-13C
CAS No.	3881-06-9
Molecular Formula	13CH3COCH3
Molecular Weight	59.06 g/mol
Synonyms	Acetone-2-13C; (2-13C)Acetone; 2-Propanone-2-13C; 13C-Labeled Acetone; Isotopic Acetone; Dimethyl ketone-2-13C; Propanone-2-13C; Acetone (carbon-13C)
EINECS	Contact for details

Quality Control

Our Acetone-2-13C is produced under controlled conditions to ensure exceptional isotopic and chemical purity, meeting the stringent requirements of analytical and research applications. Each batch is supported by a comprehensive Certificate of Analysis (COA) detailing parameters such as isotopic enrichment, chemical purity (by GC), and solvent content. We adhere to rigorous quality management practices, and specifications can be tailored to meet specific research or compendial needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, well-ventilated area away from heat, sparks, and open flames. Due to its highly volatile nature, ensure containers are kept upright and sealed when not in use. Recommended storage temperature is 2-8°C for long-term stability, although it can be stored at controlled room temperature (15-25°C) for shorter periods.

Specification

Item	Specification
Appearance	Colorless clear liquid
Identification (IR)	Conforms to structure
Isotopic Enrichment	≥ 99 atom % 13C
Chemical Purity (GC)	≥ 99.5%
Water Content (KF)	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.