Description

2-Naphthyl Triflate is a high-purity organotriflate reagent, also known as 2-Naphthyl Trifluoromethanesulfonate, widely used in advanced organic synthesis. Its primary value lies in its exceptional reactivity as a robust leaving group, facilitating efficient cross-coupling reactions and nucleophilic substitutions. This compound is essential for researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials sectors who require reliable building blocks for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate Synthesis: A key reagent in the synthesis of active pharmaceutical ingredients (APIs), particularly in palladium-catalyzed cross-coupling reactions like Suzuki, Negishi, and Stille couplings.
• Agrochemical Development: Used in creating novel herbicides, fungicides, and insecticides by introducing the naphthyl moiety into target molecules.
• Ligand and Catalyst Preparation: Serves as a precursor for synthesizing specialized phosphine ligands and organometallic catalysts.
• Material Science Research: Employed in the development of organic semiconductors, liquid crystals, and conductive polymers where the naphthalene structure is integral.
• Fine Chemical Manufacturing: Utilized in multi-step synthetic routes for producing dyes, pigments, and specialty performance chemicals.
• Academic & R&D Laboratories: A valuable tool for methodological development in organic chemistry and exploring new reaction pathways.

Basic Information

Product Name	2-Naphthyl Triflate
CAS No.	3857-83-8
Molecular Formula	C11H7F3O3S
Molecular Weight	276.23 g/mol
Synonyms	2-Naphthyl Trifluoromethanesulfonate; 2-Naphthyl Triflate; β-Naphthyl Triflate; Naphthalen-2-yl Trifluoromethanesulfonate; 2-Naphthalenyl Trifluoromethanesulfonate; 2-(Trifluoromethanesulfonyloxy)naphthalene; Trifluoromethanesulfonic Acid 2-Naphthyl Ester
EINECS	223-381-6

Quality Control

Our 2-Naphthyl Triflate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC analysis, to ensure high chemical purity and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing purity, identity, and impurity profiles to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Melting Point	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.