Description

1,3,5-Tris-Chloromethyl-2,4,6-Trimethyl-Benzene is a key aromatic intermediate featuring three reactive chloromethyl groups on a mesitylene core. This compound matters for its versatility as a trifunctional building block, enabling the synthesis of complex molecular architectures, dendrimers, and cross-linked polymers. It is needed by R&D chemists and process engineers in the pharmaceutical, agrochemical, and advanced materials industries for constructing novel compounds and functional polymers.

Application

• Pharmaceutical Intermediate: Serves as a crucial trifunctional scaffold for the synthesis of novel active pharmaceutical ingredients (APIs) and complex drug candidates.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and pesticides requiring a rigid, multi-branching core structure.
• Dendrimer & Polymer Chemistry: Acts as a core monomer for constructing star-shaped polymers, hyperbranched polymers, and dendrimers with precise functionality.
• Cross-linking Agent: Employed in the manufacture of thermosetting resins, epoxy hardeners, and high-performance coatings to enhance mechanical and thermal properties.
• Ligand & Catalyst Precursor: Utilized to synthesize multidentate ligands for metal-organic frameworks (MOFs) and homogeneous catalysis.
• Organic Synthesis Building Block: Provides a versatile platform for nucleophilic substitution reactions to introduce various functional groups in a controlled manner.

Basic Information

Product Name	1,3,5-Tris-Chloromethyl-2,4,6-Trimethyl-Benzene
CAS No.	3849-01-2
Molecular Formula	C12H15Cl3
Molecular Weight	273.60 g/mol
Synonyms	1,3,5-Tris(chloromethyl)-2,4,6-trimethylbenzene; 1,3,5-Tris(chloromethyl)mesitylene; Mesitylene-1,3,5-triyltrimethyl trichloride; Tris(chloromethyl)mesitylene; 2,4,6-Trimethyl-1,3,5-tris(chloromethyl)benzene; TCTMB; 1,3,5-Tri(chloromethyl)-2,4,6-trimethylbenzene
EINECS	223-357-6

Quality Control

Our 1,3,5-Tris-Chloromethyl-2,4,6-Trimethyl-Benzene undergoes rigorous quality testing to ensure compliance with industry standards. We provide comprehensive analytical data, including HPLC purity, identity confirmation (IR, NMR), and impurity profiling. Certificates of Analysis (COA) are available for every batch upon request, detailing all relevant specifications to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, open flames, and incompatible materials such as strong bases and oxidizing agents. Due to its light-sensitive nature, containers should be amber-colored or stored in dark conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	105 - 110 °C
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.