Description

Ketone, Cyclopropyl Fluoromethyl (7Ci,8Ci) is a specialized fluorinated ketone building block with the CAS registry number 3794-04-5. This compound is valued for its unique structural motif, combining a reactive ketone group with a cyclopropyl ring and a fluoromethyl substituent, making it a versatile intermediate for advanced synthetic chemistry. It is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and complex molecular architectures.

Application

• Pharmaceutical Intermediate: Serves as a key synthon in the research and development of new drug candidates, particularly those targeting central nervous system (CNS) disorders or requiring fluorinated motifs for metabolic stability.
• Agrochemical Synthesis: Used in the creation of novel herbicides, fungicides, and insecticides where the cyclopropyl and fluorine groups can enhance biological activity and environmental persistence.
• Material Science Research: Acts as a precursor for specialty monomers or ligands in the development of advanced polymers, coatings, or catalytic systems.
• Fluorine Chemistry: A valuable substrate for studying fluorination reactions, ring-opening transformations of strained cyclopropanes, and the synthesis of other fluorinated fine chemicals.
• Academic & Contract Research: Employed in university and CRO (Contract Research Organization) laboratories for methodological studies and the exploration of new chemical spaces.

Basic Information

Product Name	Ketone, Cyclopropyl Fluoromethyl (7Ci,8Ci)
CAS No.	3794-04-5
Molecular Formula	C5H7FO
Molecular Weight	102.11 g/mol
Synonyms	Cyclopropyl fluoromethyl ketone; 1-Cyclopropyl-2-fluoroethanone; 2-Fluoro-1-cyclopropylethanone; Fluoromethyl cyclopropyl ketone; (Fluoromethyl)cyclopropyl ketone; 3794-04-5; NSC 406916
EINECS	Contact for details

Quality Control

Every batch of Ketone, Cyclopropyl Fluoromethyl (7Ci,8Ci) is produced and analyzed under strict quality management protocols. Our products undergo rigorous quality testing, including chromatographic purity analysis and structural confirmation, to ensure consistency and compliance with research-grade standards. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and physical properties is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Due to its classification as a fluoride/strong alkali reactive and highly volatile compound, store in a cool, well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, open flames, and incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 95.0% (Research Grade)
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.