Description

2-Methylenesuccinamide is a versatile, high-purity chemical intermediate with significant utility in advanced organic synthesis. This compound is valued for its reactive methylene group and amide functionalities, enabling its use in the creation of complex molecules and specialty polymers. It serves as a critical building block for researchers and manufacturers in the pharmaceutical, agrochemical, and polymer industries seeking to develop novel compounds and materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs) and novel drug candidates, particularly those requiring succinimide or maleimide derivatives.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and plant growth regulators, contributing to the development of new crop protection solutions.
• Polymer & Resin Modifier: Acts as a cross-linking agent or comonomer in specialty polymer formulations to enhance thermal stability, adhesion, or mechanical properties.
• Bioconjugation Chemistry: Utilized in the preparation of maleimide-functionalized linkers for protein and antibody-drug conjugate (ADC) development.
• Organic Synthesis Building Block: Employed in Michael addition reactions, cyclizations, and other transformations to construct heterocyclic compounds and complex organic architectures.
• Research & Development: Serves as a valuable reagent in academic and industrial R&D labs for exploring new chemical reactions and material science applications.

Basic Information

Product Name	2-Methylenesuccinamide
CAS No.	3786-29-6
Molecular Formula	C5H8N2O2
Molecular Weight	128.13 g/mol
Synonyms	2-Methylenebutanediamide; 2-Methylenesuccinic acid diamide; Itaconamide; Methylenesuccinamide; 2-Methylenesuccinic Diamide; Itaconic Acid Diamide; 2-Methylenebutane-1,4-diamide
EINECS	223-258-5

Quality Control

Our 2-Methylenesuccinamide is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets exacting standards for research and industrial use. A detailed Certificate of Analysis (COA) is provided with each shipment, guaranteeing traceability and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under dry conditions to prevent degradation. Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.