Description

2-(Bromomethyl)-1-Chloro-4-Methoxybenzene is a versatile halogenated aromatic building block of significant importance in advanced organic synthesis. Its molecular structure, featuring both bromomethyl and chloro substituents on a methoxybenzene ring, makes it a key intermediate for constructing complex molecules. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for the development of active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of various active pharmaceutical ingredients (APIs), particularly those requiring functionalized benzyl or aryl ether motifs.
• Agrochemical Synthesis: Used in the production of herbicides, fungicides, and insecticides, where its halogenated structure allows for further derivatization.
• Ligand and Catalyst Development: Employed in the preparation of specialized ligands for metal-catalyzed cross-coupling reactions and other catalytic processes.
• Material Science Research: Acts as a monomer or functionalizing agent in the development of advanced polymers and liquid crystals.
• Chemical Research & Development: A valuable reagent for exploring novel organic reactions and constructing complex molecular architectures in academic and industrial R&D labs.

Basic Information

Product Name	2-(Bromomethyl)-1-Chloro-4-Methoxybenzene
CAS No.	3771-13-9
Molecular Formula	C8H8BrClO
Molecular Weight	235.51 g/mol
Synonyms	1-Chloro-2-(bromomethyl)-4-methoxybenzene; 4-Chloro-3-(bromomethyl)anisole; 2-Bromomethyl-4-chloroanisole; 4-Methoxy-2-(bromomethyl)chlorobenzene; (2-Bromomethyl)-4-chloro-1-methoxybenzene; 1-Methoxy-4-chloro-2-(bromomethyl)benzene; Benzene, 2-(bromomethyl)-1-chloro-4-methoxy-; 3771-13-9
EINECS	223-228-2

Quality Control

Our 2-(Bromomethyl)-1-Chloro-4-Methoxybenzene is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided and available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.