Description

(3S)-3,4-Dihydro-7-Methoxy-3-(4-Methoxyphenyl)-2H-1-Benzopyran is a high-purity chiral chromane derivative, a key structural motif in medicinal chemistry. This compound is valued for its role as a sophisticated synthetic intermediate and a potential pharmacophore in active pharmaceutical ingredient (API) development. It is primarily sought by research institutions and pharmaceutical companies engaged in the synthesis of novel therapeutic agents, particularly in areas requiring specific stereochemistry.

Application

• Pharmaceutical Intermediate: Serves as a critical building block for the synthesis of complex drug candidates, especially those targeting central nervous system (CNS) and cardiovascular diseases.
• Medicinal Chemistry Research: Used as a core scaffold in structure-activity relationship (SAR) studies to develop new molecules with optimized biological activity.
• Chiral Synthesis: Utilized in asymmetric synthesis due to its defined (3S) stereochemistry, enabling the production of enantiomerically pure compounds.
• Reference Standard: Employed as an analytical standard in quality control laboratories for method development and impurity profiling.
• Chemical Biology Probes: Acts as a starting material for creating molecular probes to study enzyme mechanisms and biological pathways.

Basic Information

Product Name	(3S)-3,4-Dihydro-7-Methoxy-3-(4-Methoxyphenyl)-2H-1-Benzopyran
CAS No.	3722-56-3
Molecular Formula	C17H18O3
Molecular Weight	270.32 g/mol
Synonyms	(S)-7-Methoxy-3-(4-methoxyphenyl)chroman; (3S)-7-Methoxy-3-(4-methoxyphenyl)-3,4-dihydro-2H-1-benzopyran; (S)-3-(4-Methoxyphenyl)-7-methoxychroman; (S)-3,4-Dihydro-7-methoxy-3-(4-methoxyphenyl)-2H-chromene; (3S)-3-(4-Methoxyphenyl)-7-methoxy-3,4-dihydro-2H-chromene; (S)-(-)-7-Methoxy-3-(4-methoxyphenyl)chroman; (S)-3-(p-Methoxyphenyl)-7-methoxychroman
EINECS	Contact for details

Quality Control

Our (3S)-3,4-Dihydro-7-Methoxy-3-(4-Methoxyphenyl)-2H-1-Benzopyran is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including chiral purity verification, to ensure it meets the stringent requirements for pharmaceutical R&D. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming identity, purity, and other critical parameters.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (Chiral HPLC)	≥99.0% ee
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.