Description

5,6,7,8-Tetrahydro-1H-2-Benzopyran-1,3(4H)-Dione is a versatile bicyclic lactone and dione compound that serves as a critical synthetic intermediate in advanced organic chemistry. Its unique fused ring structure makes it a valuable building block for constructing complex molecular architectures, particularly in pharmaceutical research and fine chemical synthesis. This high-purity intermediate is essential for R&D chemists and process development scientists working in pharmaceutical, agrochemical, and specialty chemical industries who require reliable, high-quality building blocks for their synthetic routes.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and cardiovascular targets.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and plant growth regulators due to its reactive carbonyl and lactone functionalities.
• Fine Chemical Production: Serves as a building block for dyes, pigments, and performance chemicals where its bicyclic structure imparts specific physical properties.
• Academic & Industrial R&D: Employed in methodological chemistry research for studying cyclization reactions, ring transformations, and as a model substrate in catalysis studies.
• Material Science Precursor: Potential use in the synthesis of organic ligands for metal-organic frameworks (MOFs) and other advanced polymeric materials.

Basic Information

Product Name	5,6,7,8-Tetrahydro-1H-2-Benzopyran-1,3(4H)-Dione
CAS No.	3711-74-8
Molecular Formula	C9H10O3
Molecular Weight	166.17 g/mol
Synonyms	1,3-Dioxo-5,6,7,8-tetrahydro-1H-2-benzopyran; 5,6,7,8-Tetrahydro-2H-1-benzopyran-1,3-dione; 3,4-Dihydro-1H-2-benzopyran-1,3(5H)-dione; Tetrahydro-1H-2-benzopyran-1,3(4H)-dione; 1,3(4H)-Dioxo-5,6,7,8-tetrahydro-2-benzopyran; 5,6,7,8-Tetrahydrocoumarin-1,3-dione
EINECS	223-059-5

Quality Control

Our 5,6,7,8-Tetrahydro-1H-2-Benzopyran-1,3(4H)-Dione is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Production follows current Good Manufacturing Practices (cGMP) where applicable, and the material is subjected to rigorous analytical testing including HPLC, GC, and NMR. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). The compound may be light-sensitive; prolonged exposure to light should be avoided. Keep away from strong oxidizing agents, strong bases, and sources of ignition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.