Description

4-(4-Chloro-Phenyl)-Tetrahydro-Pyran-4-Carboxylic Acid is a versatile and high-purity chemical intermediate characterized by its unique pyran ring structure substituted with a chlorophenyl group. This compound matters for its role as a critical building block in the synthesis of complex molecules, offering a defined chiral center and functional handles for further derivatization. It is primarily needed by research institutions and manufacturers in the pharmaceutical and agrochemical industries for developing new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and anti-inflammatory targets.
• Agrochemical Synthesis: Used in the research and development of advanced herbicides, fungicides, and plant growth regulators.
• Ligand and Catalyst Development: Serves as a scaffold for creating chiral ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the development of specialty polymers and advanced organic materials with specific optical or electronic properties.
• Academic & R&D: A valuable compound for methodological studies in organic chemistry and medicinal chemistry research programs.
• Custom Synthesis: The starting point for contract manufacturing organizations (CMOs) to produce bespoke compounds for client projects.

Basic Information

Product Name	4-(4-Chloro-Phenyl)-Tetrahydro-Pyran-4-Carboxylic Acid
CAS No.	3648-57-5
Molecular Formula	C12H13ClO3
Molecular Weight	240.68 g/mol
Synonyms	4-(4-Chlorophenyl)tetrahydro-2H-pyran-4-carboxylic acid; 4-(p-Chlorophenyl)tetrahydropyran-4-carboxylic Acid; 4-(4-Chlorophenyl)-4-carboxytetrahydropyran; 4-Carboxy-4-(4-chlorophenyl)tetrahydropyran; 4-(4-Chlorophenyl)oxane-4-carboxylic acid; 4-(4-Chloro-phenyl)-tetrahydro-pyran-4-carboxylic acid; 4-(4-Chlorophenyl)tetrahydropyran-4-carboxylic acid; 4-(4-Chlorophenyl)-4-piperidinecarboxylic acid, tetrahydro-2H-pyran analog
EINECS	Contact for details

Quality Control

Our 4-(4-Chloro-Phenyl)-Tetrahydro-Pyran-4-Carboxylic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The container should be kept tightly sealed in a dry environment to minimize exposure to moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.