Description

1-Hydroxy-2,2,6,6-tetramethyl-4-oxopiperidine is a versatile hindered amine derivative that serves as a key intermediate and functional additive in advanced chemical synthesis. Its unique piperidinone structure provides significant value as a nitroxide radical precursor and a stabilizer against oxidative degradation. This compound is essential for manufacturers in the polymer, pharmaceutical, and specialty chemical industries seeking to enhance product longevity and performance.

Application

• Polymer Stabilizer: Acts as a precursor for Hindered Amine Light Stabilizers (HALS) and antioxidants, protecting plastics and coatings from UV-induced degradation.
• Pharmaceutical Intermediate: Used in the synthesis of complex molecules, including potential active pharmaceutical ingredients (APIs) and nitroxide-based contrast agents.
• Organic Synthesis Building Block: Serves as a key scaffold for constructing more complex heterocyclic compounds and ligands in catalytic systems.
• Nitroxide Radical Source: Utilized in controlled/living radical polymerization (e.g., NMP) and as a spin label or probe in biochemical and materials research.
• Fuel & Lubricant Additive: Functions as an antioxidant additive to prevent gum formation and oxidative breakdown in fuels and industrial lubricants.
• Rubber & Elastomer Stabilization: Imparts resistance to heat and oxygen, extending the service life of rubber products.

Basic Information

Product Name	1-Hydroxy-2,2,6,6-tetramethyl-4-oxopiperidine
CAS No.	3637-11-4
Molecular Formula	C9H17NO2
Molecular Weight	171.24 g/mol
Synonyms	1-Hydroxy-2,2,6,6-tetramethylpiperidin-4-one; 4-Oxo-2,2,6,6-tetramethyl-1-hydroxypiperidine; 2,2,6,6-Tetramethyl-4-oxo-1-piperidinol; 4-Oxo-TEMPO; 4-Oxo-2,2,6,6-tetramethylpiperidine-1-oxyl precursor; 1-Hydroxy-4-oxo-2,2,6,6-tetramethylpiperidine; TEMPONE precursor; HTMP
EINECS	222-882-7

Quality Control

Our 1-Hydroxy-2,2,6,6-tetramethyl-4-oxopiperidine is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with agreed specifications. We support customer audits and can provide material for qualification under cGMP or ISO 9001 frameworks as required.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic and easily oxidized nature, it is recommended to store the product under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation and to minimize moisture uptake. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 98.0%
Melting Point	72 - 76 °C
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.