Description

1-(p-Tosyl)Aziridine is a versatile and highly reactive aziridine derivative, primarily used as a key synthetic intermediate in organic chemistry. Its value lies in its ability to act as an electrophilic alkylating agent, facilitating the introduction of the tosyl-protected aziridine moiety into complex molecular frameworks. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries, particularly for the synthesis of active pharmaceutical ingredients (APIs), ligands, and functional polymers.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of novel drug candidates, especially those containing nitrogen heterocycles.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides due to its reactive three-membered ring.
• Polymer Modification: Serves as a cross-linking agent or functional monomer for creating polymers with specific chemical or physical properties.
• Bioconjugation Chemistry: Employed in the modification of proteins, peptides, and other biomolecules for research and diagnostic applications.
• Material Science Research: Utilized in the development of advanced materials, including coatings and adhesives.
• Academic & R&D Laboratories: A valuable reagent for methodological development and exploratory organic synthesis.

Basic Information

Product Name	1-(p-Tosyl)Aziridine
CAS No.	3634-89-7
Molecular Formula	C9H11NO2S
Molecular Weight	197.25 g/mol
Synonyms	N-(p-Toluenesulfonyl)aziridine; 1-Tosylaziridine; N-Tosylaziridine; Aziridine, 1-(4-methylphenyl)sulfonyl-; Tosyl Aziridine; p-Toluenesulfonyl Aziridine; 2-(4-Methylphenylsulfonyl)aziridine; 1-(4-Methylbenzenesulfonyl)aziridine
EINECS	222-870-3

Quality Control

Our 1-(p-Tosyl)Aziridine is manufactured under strict quality management protocols. Each batch undergoes comprehensive analytical testing to ensure high purity and consistency. We provide detailed Certificates of Analysis (COA) that include data from HPLC, NMR, and other relevant spectroscopic methods. Our quality commitment ensures the material meets the stringent requirements for research and commercial synthesis applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for prolonged storage or after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	68 - 72 °C
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.