Description

3-Chloro-2-Methylbenzenesulfonamide is a versatile sulfonamide derivative serving as a critical building block in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of pharmaceuticals, agrochemicals, and functional materials, where its unique benzenesulfonamide core enables precise molecular modifications. It is primarily needed by research and development chemists, process development scientists, and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries seeking to create novel active compounds.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs targeting specific enzymes or receptors where the sulfonamide group is a crucial pharmacophore.
• Agrochemical Synthesis: Used in the development of new herbicides, fungicides, and insecticides, leveraging its halogenated aromatic structure for bioactivity.
• Chemical Research & Development: Serves as a versatile scaffold in medicinal chemistry for structure-activity relationship (SAR) studies and the discovery of new bioactive molecules.
• Dye and Pigment Manufacturing: Acts as an intermediate in the production of specialized dyes and pigments, where the sulfonamide group can influence color properties and solubility.
• Polymer Modification: Can be utilized to introduce functional groups into polymer chains, altering material properties like hydrophilicity or reactivity for advanced material science applications.
• Ligand for Catalysis: Potential use in designing ligands for metal-catalyzed reactions due to the coordinating ability of the sulfonamide nitrogen.

Basic Information

Product Name	3-Chloro-2-Methylbenzenesulfonamide
CAS No.	3476-03-7
Molecular Formula	C7H8ClNO2S
Molecular Weight	205.66 g/mol
Synonyms	2-Methyl-3-chlorobenzenesulfonamide; 3-Chloro-o-toluenesulfonamide; 1-Chloro-2-methyl-6-sulfamoylbenzene; Benzenesulfonamide, 3-chloro-2-methyl-; 3-Chloro-2-methylbenzene-1-sulfonamide; o-Toluenesulfonamide, 3-chloro-; NSC 403107
EINECS	Contact for details

Quality Control

Our 3-Chloro-2-Methylbenzenesulfonamide is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by IR and NMR spectroscopy, to ensure it meets the high standards required for synthetic applications. A comprehensive Certificate of Analysis (COA) detailing purity, impurity profile, and physical characteristics is provided with every shipment to guarantee traceability and batch-to-batch consistency for your critical processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents. The container should be kept tightly sealed to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.