Description

(1R)-2α-Phenylcyclopropane-1β-Carboxylic Acid CAS NO 3471-10-1 is a high-purity, chiral cyclopropane derivative, a key building block in advanced organic synthesis. Its rigid, three-membered ring structure and defined stereochemistry make it a valuable intermediate for constructing complex molecules with precise spatial orientation. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, where it is used to create novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A crucial chiral synthon for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of central nervous system (CNS) drugs and enzyme inhibitors.
• Agrochemical Research: Used in the creation of novel herbicides, fungicides, and insecticides, where its cyclopropane core contributes to biological activity and metabolic stability.
• Ligand and Catalyst Development: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis to control stereoselectivity.
• Material Science: Employed in the research of advanced polymers and liquid crystals, where its structural rigidity can influence material properties.
• Academic & Contract Research: A valuable reagent for methodological studies in organic chemistry, including cyclopropanation reactions and stereochemistry investigations.

Basic Information

Product Name	(1R)-2α-Phenylcyclopropane-1β-Carboxylic Acid
CAS No.	3471-10-1
Molecular Formula	C10H10O2
Molecular Weight	162.19 g/mol
Synonyms	(1R,2S)-2-Phenylcyclopropanecarboxylic Acid; (1R,2S)-2-Phenylcyclopropane-1-carboxylic Acid; trans-2-Phenylcyclopropanecarboxylic Acid; (1R,2S)-2-Phenylcyclopropanecarboxylic Acid; (1R,2S)-PCCA; (1R)-2-Phenylcyclopropanecarboxylic Acid; (1R,2S)-2-Phenyl-1-cyclopropanecarboxylic Acid; (+)-(1R,2S)-2-Phenylcyclopropanecarboxylic Acid
EINECS	Contact for details

Quality Control

Our (1R)-2α-Phenylcyclopropane-1β-Carboxylic Acid is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including chiral purity analysis by HPLC, to ensure high enantiomeric excess (ee) and chemical purity. A detailed Certificate of Analysis (COA) providing specifications for identity, assay, and impurities is provided with each shipment to guarantee consistent quality and traceability for your critical R&D and production processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong acids and organic solvents. For long-term storage under inert atmosphere, please contact our technical team for specific recommendations.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.