Description

Dehydrodeguelin is a naturally occurring rotenoid compound, a derivative of deguelin, known for its potent biological activity. This high-purity intermediate is critical for research and development in life sciences, particularly in the study of cellular pathways and molecular mechanisms. It serves as a valuable building block for pharmaceutical research, agrochemical development, and advanced biochemical studies targeting specific enzymes and receptors.

Application

• Pharmaceutical Research & Development: As a key reference standard and active intermediate in the discovery of novel therapeutic agents, particularly in oncology and metabolic disease research.
• Biochemical Research: Used as a potent inhibitor in mechanistic studies of mitochondrial complex I and other NADH-ubiquinone oxidoreductase pathways.
• Agrochemical Studies: Investigated for its potential as a lead compound in the development of next-generation, naturally derived insecticides and acaricides.
• Academic Research: A crucial tool compound for universities and research institutes studying apoptosis, cell signaling, and natural product chemistry.
• Reference Standard Manufacturing: Sourced by laboratories and companies that produce certified reference materials (CRMs) for analytical and quality control purposes.

Basic Information

Product Name	Dehydrodeguelin
CAS No.	3466-23-7
Molecular Formula	C23H20O6
Molecular Weight	392.40 g/mol
Synonyms	13,13a-Dehydrodeguelin; (-)-Dehydrodeguelin; 7a,13a-Dehydrodeguelin; Tephrosin precursor; Rotenoid derivative; Deguelin quinone; NSC 374128
EINECS	Contact for details

Quality Control

Our Dehydrodeguelin is produced under a strict quality management system to ensure batch-to-batch consistency and high purity for research applications. Each lot is analyzed using advanced chromatographic and spectroscopic techniques, including HPLC, GC-MS, and NMR, to confirm identity and potency. A comprehensive Certificate of Analysis (COA) detailing purity, related substances, and residual solvents is provided with every shipment to support your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to maintain stability.

Specification

Item	Specification
Appearance	Yellow to light brown powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Related Substances (HPLC)	Total impurities ≤ 5.0%
Loss on Drying	≤ 2.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.