Description

Methyl 3-(Chloroformyl)Benzoate is a versatile and highly reactive aromatic ester-acid chloride intermediate. Its bifunctional nature, featuring both an ester and a highly electrophilic acid chloride group, makes it a critical building block for synthesizing complex molecules. This compound is essential for research and production in the pharmaceutical, agrochemical, and advanced materials sectors, where it is used to introduce the 3-(methoxycarbonyl)benzoyl moiety.

Application

• Pharmaceutical Intermediates: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds targeting metabolic and central nervous system disorders.
• Agrochemical Synthesis: Used to construct novel herbicides, fungicides, and plant growth regulators by forming amide or ester linkages.
• Liquid Crystal & Polymer Chemistry: Serves as a monomer or cross-linking agent for creating specialized polymers and liquid crystal materials with specific optical properties.
• Organic Synthesis & Research: A valuable reagent in academic and industrial R&D for constructing complex aromatic esters, ketones, and amides via Friedel-Crafts acylation or nucleophilic substitution reactions.
• Dye & Pigment Manufacturing: Intermediate in the production of specialized dyes and organic pigments, contributing to color fastness and molecular stability.
• Peptide Mimetics & Bio-conjugation: Employed to modify peptides or create peptide-like structures for drug discovery and biochemical probes.

Basic Information

Product Name	Methyl 3-(Chloroformyl)Benzoate
CAS No.	3441-03-0
Molecular Formula	C9H7ClO3
Molecular Weight	198.60 g/mol
Synonyms	3-(Methoxycarbonyl)benzoyl chloride; Methyl 3-chlorocarbonylbenzoate; Isophthalic acid monomethyl ester chloride; 3-Carbomethoxybenzoyl chloride; m-(Methoxycarbonyl)benzoyl chloride; Benzoic acid, 3-(chlorocarbonyl)-, methyl ester; Methyl m-chloroformylbenzoate
EINECS	222-340-9

Quality Control

Our Methyl 3-(Chloroformyl)Benzoate is manufactured under a strict quality management system. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical parameters. Our production adheres to cGMP guidelines where applicable, ensuring reliability for sensitive pharmaceutical and fine chemical synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic and moisture-sensitive nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent hydrolysis. Keep away from heat, open flames, and incompatible materials such as strong bases, alcohols, and amines.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (Karl Fischer)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.