Description

3-Hydroxy-1-Methyleneandrostan-17-One is a high-purity steroid intermediate of significant importance in advanced pharmaceutical synthesis. This compound matters as a key building block for the development of novel therapeutic agents, particularly in the fields of endocrinology and metabolic research. It is primarily needed by R&D laboratories and production facilities in the pharmaceutical and biotechnology industries for the synthesis of specialized steroid-based active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of advanced steroid-based active pharmaceutical ingredients (APIs).
• Research & Development: Used in academic and industrial laboratories for the discovery and development of new therapeutic compounds targeting hormonal pathways.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method validation in pharmaceutical analysis.
• Biochemical Research: Employed in studies investigating steroid metabolism, receptor binding, and enzyme inhibition.
• Process Chemistry: Utilized in scaling up synthetic routes from laboratory to pilot plant and commercial manufacturing scales.

Basic Information

Product Name	3-Hydroxy-1-Methyleneandrostan-17-One
CAS No.	3398-66-1
Molecular Formula	C₂₀H₂₈O₂
Molecular Weight	300.44 g/mol
Synonyms	1-Methylene-3-hydroxyandrostan-17-one; 17-Oxo-1-methylen-3-hydroxyandrostane; 3-Hydroxy-1-methyleneandrostan-17-one; 1-Dehydrotestololactone; NSC 10481; 1-Methylen-3-hydroxy-17-androstanon; 1-Methylene-3-hydroxy-17-androstanone
EINECS	Contact for details

Quality Control

Our 3-Hydroxy-1-Methyleneandrostan-17-One is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation by IR and NMR spectroscopy, to ensure it meets the high standards required for pharmaceutical R&D and synthesis. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.