Description

n-Carbamoylmaleimide is a versatile heterocyclic building block and Michael acceptor, essential for advanced organic synthesis. Its bifunctional nature, featuring both a reactive maleimide double bond and a carbamoyl group, makes it a critical intermediate for constructing complex molecular architectures. This compound is primarily utilized by researchers and manufacturers in the pharmaceutical, agrochemical, and polymer industries for developing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of biologically active molecules, including potential enzyme inhibitors and anticancer agents.
• Polymer Modification: Used as a cross-linking agent or comonomer to introduce reactive sites and enhance the properties of specialty polymers and resins.
• Bioconjugation Chemistry: Acts as a linker for coupling biomolecules (e.g., peptides, proteins) due to the selective reactivity of the maleimide group with thiols.
• Agrochemical Synthesis: Employed in the research and development of new herbicides, fungicides, and plant growth regulators.
• Material Science Research: Utilized in creating advanced organic frameworks, dendrimers, and other functional materials with tailored properties.
• Chemical Biology Probes: Functions as a scaffold for developing activity-based probes and diagnostic agents.

Basic Information

Product Name	n-Carbamoylmaleimide
CAS No.	3345-50-4
Molecular Formula	C5H4N2O3
Molecular Weight	140.10 g/mol
Synonyms	Maleamic acid N-carboxyanhydride; 1H-Pyrrole-2,5-dione, 3-carbamoyl-; 3-Carbamoyl-1H-pyrrole-2,5-dione; Carbamoylmaleimide; N-(2,5-Dioxo-2,5-dihydro-1H-pyrrol-3-yl)formamide
EINECS	222-115-6

Quality Control

Our n-Carbamoylmaleimide is produced under stringent quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via FT-IR and NMR spectroscopy, to ensure it meets the high standards required for research and industrial synthesis. A detailed Certificate of Analysis (COA) is provided with every shipment to guarantee traceability, consistency, and reliability.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). This compound may be moisture-sensitive; keep the container tightly sealed when not in use.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.