Description

iso-Malathion is a specific stereoisomer of the widely used organophosphate insecticide, Malathion, identified by the CAS registry number 3344-12-5. This compound is of significant interest in research and development for its distinct biological activity and physicochemical properties compared to the technical mixture. It serves as a critical reference standard and intermediate for scientists and manufacturers in the agrochemical and pharmaceutical sectors who require high-purity, well-characterized chemical entities for analytical, synthetic, and toxicological studies.

Application

• Analytical Reference Standard: Primary use as a certified reference material (CRM) for calibrating equipment and validating analytical methods (e.g., HPLC, GC-MS) in quality control and regulatory testing.
• Metabolite and Degradation Studies: Essential for investigating the environmental fate, metabolic pathways, and breakdown products of malathion in ecological and toxicological research.
• Biochemical Research: Used in enzymatic studies to understand the specific interaction and inhibition mechanism of acetylcholinesterase by individual malathion isomers.
• Agrochemical R&D: Acts as a key intermediate or pure component in the development and synthesis of new insecticidal formulations with optimized efficacy and safety profiles.
• Pharmaceutical Impurity Profiling: Employed in the identification and quantification of isomeric impurities in active pharmaceutical ingredients (APIs) where malathion or related structures are relevant.
• Toxicological Assessment: Crucial for conducting precise toxicology and ecotoxicology studies to determine the specific effects of the iso-malathion isomer.

Basic Information

Product Name	iso-Malathion
CAS No.	3344-12-5
Molecular Formula	C10H19O6PS2
Molecular Weight	330.36 g/mol
Synonyms	Iso-malathion; (1,2-Dicarbethoxyethyl) O,O-dimethyl phosphorodithioate (isomer); Diethyl (dimethoxyphosphinothioylthio)succinate (isomer); S-[1,2-Bis(ethoxycarbonyl)ethyl] O,O-dimethyl phosphorodithioate (isomer); Malathion impurity; Malathion isomer; O,O-Dimethyl S-1,2-dicarbethoxyethyl phosphorodithioate (isomer); Mercaptosuccinic acid diethyl ester O,O-dimethyl phosphorodithioate (isomer)
EINECS	Contact for details

Quality Control

Our iso-Malathion CAS 3344-12-5 is produced and handled under strict quality management protocols. Each batch undergoes rigorous analytical testing, including chromatographic purity assays and identity confirmation, to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay results, and analytical methods is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. For long-term storage under inert atmosphere, please contact our technical team for specific recommendations.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0% (Area %)
Assay (Titration)	Contact for details
Related Substances (HPLC)	Individual impurity ≤ 1.0%
Water Content (KF)	≤ 0.5%
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.