Description

n-(4,5-Dihydro-5-Oxo-1-Phenyl-1H-Pyrazol-3-Yl)Methacrylamide is a specialized methacrylamide derivative featuring a pyrazolone core, designed for advanced polymer synthesis and functional material development. This compound is valued for its ability to introduce reactive polymerizable groups and specific heterocyclic functionality into macromolecular chains, enabling the creation of materials with tailored properties. It is primarily sought by R&D chemists and process engineers in the pharmaceutical intermediates, advanced polymer, and specialty chemical sectors for developing novel copolymers, coatings, and bioactive conjugates.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of active pharmaceutical ingredients (APIs) and drug conjugates, particularly those requiring a polymerizable handle for targeted delivery systems.
• Functional Monomer for Advanced Polymers: Used as a co-monomer to incorporate pyrazolone moieties into acrylic and methacrylic polymer backbones, imparting specific chemical reactivity, UV-absorption, or chelating properties.
• Specialty Coatings and Adhesives: Enhances the performance of industrial coatings, adhesives, and inks by contributing to cross-linking density, adhesion promotion, and thermal stability.
• Research & Development: A valuable reagent in academic and industrial R&D for exploring new polymer architectures, smart materials, and chemical biology tools.
• Chelating Resin Precursor: Acts as a precursor in the manufacture of ion-exchange or chelating resins for metal ion separation and recovery processes.
• Photoresist and Electronic Chemicals: Investigated for use in photoresist formulations and other electronic materials where precise polymer functionality is critical.

Basic Information

Item	Details
Product Name	n-(4,5-Dihydro-5-Oxo-1-Phenyl-1H-Pyrazol-3-Yl)Methacrylamide
CAS No.	3331-54-2
Molecular Formula	C13H13N3O2
Molecular Weight	243.26 g/mol
Synonyms	1-Phenyl-3-methacryloylamino-2-pyrazolin-5-one; 3-Methacrylamido-1-phenyl-2-pyrazolin-5-one; N-(5-Oxo-1-phenyl-4,5-dihydro-1H-pyrazol-3-yl)methacrylamide; Methacrylamide, N-(4,5-dihydro-5-oxo-1-phenyl-1H-pyrazol-3-yl)-; 1-Phenyl-3-(methacryloylamino)-5-pyrazolone; 3-Methacryloylamino-1-phenyl-5-pyrazolone; N-(1-Phenyl-5-oxo-4,5-dihydro-1H-pyrazol-3-yl)methacrylamide
EINECS	222-058-9

Quality Control

Our production of n-(4,5-Dihydro-5-Oxo-1-Phenyl-1H-Pyrazol-3-Yl)Methacrylamide adheres to stringent in-process controls and final batch testing to ensure high purity and consistent quality. Each lot is characterized using advanced analytical techniques including HPLC, NMR, and IR spectroscopy. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment, supporting compliance with cGMP and ISO 9001 standards for research and industrial use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, open flames, and incompatible materials. Due to its light-sensitive nature, containers should be opaque or stored in dark conditions to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.