Description

Boc-β-Ala-Otcp CAS NO 3303-86-4 is a protected amino acid derivative, specifically the tert-butoxycarbonyl (Boc) and trichlorophenyl (Otcp) ester derivative of β-alanine. This compound is a crucial building block in solid-phase peptide synthesis (SPPS) and organic synthesis, offering orthogonal protection strategies for the controlled elongation of peptide chains. It is primarily utilized by research institutions, pharmaceutical R&D departments, and fine chemical manufacturers involved in developing novel therapeutic peptides, peptidomimetics, and bioactive compounds.

Application

• Peptide Synthesis: A key intermediate in the solid-phase and solution-phase synthesis of peptides, particularly for incorporating β-alanine residues.
• Pharmaceutical Research: Used in the R&D of novel peptide-based drugs, hormone analogs, and diagnostic agents.
• Bioconjugation: Serves as a linker or spacer molecule in the synthesis of peptide-protein conjugates and other bioconjugates.
• Combinatorial Chemistry: Employed in the generation of peptide libraries for high-throughput screening and drug discovery.
• Fine Chemical Production: Acts as a specialized intermediate in the custom synthesis of complex organic molecules and active pharmaceutical ingredients (APIs).
• Academic Research: Utilized in university and institutional labs for studying peptide structure, function, and synthesis methodologies.

Basic Information

Product Name	Boc-β-Ala-Otcp
CAS No.	3303-86-4
Molecular Formula	C₁₄H₁₆Cl₃NO₄
Molecular Weight	368.64 g/mol
Synonyms	N-(tert-Butoxycarbonyl)-β-alanine 2,4,5-Trichlorophenyl Ester; Boc-β-Ala-OTcp; Boc-3-Aminopropanoic Acid 2,4,5-Trichlorophenyl Ester; (2,4,5-Trichlorophenoxy)carbonyl-β-alanine tert-Butyl Ester; tert-Butyl (3-((2,4,5-Trichlorophenoxy)carbonylamino)propyl)carbamate; Boc-β-Ala-O(2,4,5-Cl₃-Ph)
EINECS	Contact for details

Quality Control

Our Boc-β-Ala-Otcp is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and moisture content. Certificates of Analysis (COA) detailing all specifications are provided to ensure compliance with your research and production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C or as specified on the label. Due to its hygroscopic nature, the container should be kept sealed in a desiccated environment to prevent moisture absorption and decomposition. Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.