Description

2-Bromo-1-(1,3-thiazol-2-yl)ethanone is a versatile and reactive brominated ketone building block, crucial for advanced organic synthesis. Its core value lies in its ability to introduce the 2-acetylthiazole moiety, a key pharmacophore, into target molecules efficiently. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing novel active ingredients and complex heterocyclic compounds.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of thiazole-containing drug candidates, including kinase inhibitors and antimicrobial agents.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides that incorporate the thiazole ring system.
• Material Science Research: Serves as a precursor for functionalized polymers and advanced organic materials with specific electronic properties.
• Chemical Biology & Proteomics: Employed as a reactive handle for bioconjugation and the development of activity-based probes targeting specific enzymes.
• Academic & R&D Laboratories: A fundamental reagent for methodological development in organic chemistry and heterocyclic compound synthesis.
• Fine Chemical Production: Integral to the multi-step synthesis of complex, high-value specialty chemicals and flavors/fragrances intermediates.

Basic Information

Product Name	2-Bromo-1-(1,3-thiazol-2-yl)ethanone
CAS No.	3292-77-1
Molecular Formula	C5H4BrNOS
Molecular Weight	206.06 g/mol
Synonyms	2-Bromo-1-(thiazol-2-yl)ethanone; 2-Acetylthiazole, 2-bromo-; 2-Bromoacetylthiazole; α-Bromo-2-acetylthiazole; 2-(2-Bromoacetyl)thiazole; Ethanone, 2-bromo-1-(2-thiazolyl)-; Bromomethyl 2-thiazolyl ketone
EINECS	Contact for details

Quality Control

Every batch of 2-Bromo-1-(1,3-thiazol-2-yl)ethanone is produced and tested under strict quality management protocols to ensure consistency and reliability for your synthetic processes. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as purity (typically ≥95% by HPLC), identity confirmation, and impurity profiles. Our quality systems are designed to support cGMP and ISO standards for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Melting Point	Contact for details
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.