Description

3,4,6-Tri-o-Acetyl-α-D-Glucopyranose 1,2-(Ethyl Orthoacetate) is a key protected carbohydrate intermediate used in sophisticated organic synthesis. This compound matters because it provides a strategically functionalized glucose scaffold, enabling precise chemical modifications for advanced applications. It is primarily needed by research institutions and manufacturers in the pharmaceutical, biotechnology, and fine chemical sectors for developing novel glycosides, prodrugs, and complex bioactive molecules.

Application

• Pharmaceutical Intermediate: Critical building block for the synthesis of complex glycosides, antiviral agents, and prodrugs.
• Carbohydrate Chemistry Research: Essential reagent for academic and industrial research in glycosylation reactions and oligosaccharide assembly.
• Glycoconjugate Synthesis: Used in the preparation of glycopeptides, glycolipids, and other biologically active conjugates.
• Fine Chemical Production: Serves as a precursor for specialty chemicals, chiral auxiliaries, and advanced material science applications.
• Biochemical Tool Development: Employed in creating enzyme inhibitors, metabolic probes, and labeled sugar derivatives for biological studies.

Basic Information

Product Name	3,4,6-Tri-o-Acetyl-α-D-Glucopyranose 1,2-(Ethyl Orthoacetate)
CAS No.	3254-17-9
Molecular Formula	C16H24O11
Molecular Weight	392.36 g/mol
Synonyms	1,2-O-(1-Ethoxyethylidene)-3,4,6-tri-O-acetyl-α-D-glucopyranose; Ethyl 3,4,6-tri-O-acetyl-1,2-O-(1-ethoxyethylidene)-α-D-glucopyranoside; α-D-Glucopyranose, 3,4,6-tri-O-acetyl-, 1,2-(ethyl orthoacetate); 1,2-O-(Ethoxyethylidene)-3,4,6-tri-O-acetyl-α-D-glucopyranose; 3,4,6-Tri-O-acetyl-1,2-O-(1-ethoxyethylidene)-α-D-glucopyranose; 1,2-(Ethyl orthoacetate)-3,4,6-tri-O-acetyl-α-D-glucopyranose; Protected Glucose Orthoester; Acetylated Glucose Ethyl Orthoacetate
EINECS	221-861-4

Quality Control

Our 3,4,6-Tri-o-Acetyl-α-D-Glucopyranose 1,2-(Ethyl Orthoacetate) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and optical rotation measurement, to ensure high chemical purity and structural integrity. Certificates of Analysis (COA) detailing all specifications are available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure containers are sealed immediately after use to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Optical Rotation [α]²⁰D	+80° to +85° (c=1 in CHCl₃)
Melting Point	105°C - 110°C
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.