Description

1,2,3,4-Tetra(Methylene)Cyclobutane is a specialized, high-purity cyclic hydrocarbon building block of significant interest in advanced organic synthesis. Its unique, highly strained structure makes it a valuable precursor for developing novel polymers, pharmaceuticals, and complex molecular architectures. This compound is primarily sought by research institutions and industrial R&D departments in the pharmaceutical, agrochemical, and materials science sectors for creating innovative products with tailored properties.

Application

• Pharmaceutical Intermediate: Serves as a key synthon in the research and development of novel active pharmaceutical ingredients (APIs), particularly for creating complex, strained-ring systems.
• Polymer & Material Science: Used as a monomer or cross-linking agent for synthesizing specialty polymers with unique thermal or mechanical properties.
• Agrochemical Research: Acts as a building block in the synthesis of new-generation herbicides, fungicides, and plant growth regulators.
• Organic Synthesis Reagent: Employed in Diels-Alder reactions and other cycloadditions to construct complex polycyclic frameworks in academic and industrial laboratories.
• Ligand & Catalyst Development: Utilized for creating novel ligand systems in catalysis research for asymmetric synthesis.
• High-Energy Materials Research: Investigated as a potential component in the development of advanced fuels or propellants due to its high strain energy.

Basic Information

Product Name	1,2,3,4-Tetra(Methylene)Cyclobutane
CAS No.	3227-91-6
Molecular Formula	C8H8
Molecular Weight	104.15 g/mol
Synonyms	Tetra(methylene)cyclobutane; [4]Radialene; 1,2,3,4-Tetramethylenecyclobutane; Cyclobutane, 1,2,3,4-tetramethylene-; Tetramethylenecyclobutane; Radialene, [4]-; 1,2,3,4-Tetramethylenacyclobutane
EINECS	221-765-3

Quality Control

Our 1,2,3,4-Tetra(Methylene)Cyclobutane is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including GC, HPLC, and NMR, to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming the product meets the agreed specifications for your research or production needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area, away from heat sources and incompatible materials. For long-term storage, maintaining the material under an inert atmosphere (e.g., nitrogen or argon) in a freezer (-20°C) is recommended to preserve stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to reference spectrum
Purity (GC)	≥ 95.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.