Description

(8α)-17β-Hydroxyestr-4-En-3-One CAS NO 3218-21-1 is a high-purity steroid intermediate of significant importance in pharmaceutical synthesis. This compound serves as a critical building block for the development of advanced steroid-based active pharmaceutical ingredients (APIs). It is primarily required by research institutions and manufacturers in the pharmaceutical and biotechnology sectors engaged in hormone therapy development and advanced organic synthesis.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of steroidal drugs and hormone-based therapies.
• Research & Development: Used in academic and industrial laboratories for studying steroid metabolism and developing new chemical entities.
• Biochemical Research: Employed as a reference standard or starting material in biochemical assays and metabolic pathway studies.
• API Synthesis: Integral to the multi-step synthesis of complex steroid Active Pharmaceutical Ingredients (APIs).
• Process Chemistry: Utilized in process development and scale-up for the commercial manufacturing of steroid compounds.

Basic Information

Product Name	(8α)-17β-Hydroxyestr-4-En-3-One
CAS No.	3218-21-1
Molecular Formula	C18H26O2
Molecular Weight	274.40 g/mol
Synonyms	8α-Testosterone; 8α-Hydroxytestosterone; 17β-Hydroxy-8α-estr-4-en-3-one; 8α,17β-Dihydroxyestr-4-en-3-one; (8α)-Testosterone; 8-Epitestosterone; Estr-4-en-3-one, 17,8α-dihydroxy-; 8α-Hydroxy-17β-hydroxyestr-4-en-3-one
EINECS	Contact for details

Quality Control

Our (8α)-17β-Hydroxyestr-4-En-3-One is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing including HPLC for purity, identity confirmation by IR and NMR spectroscopy, and residual solvent analysis. A Certificate of Analysis (COA) detailing all specifications and test results is provided with every shipment to ensure traceability and compliance with your quality requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after each use to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.