Description

3-Methylene-1,4-Cyclohexadiene is a reactive diene intermediate of significant interest in synthetic organic chemistry. Its unique conjugated structure makes it a valuable building block for the synthesis of complex organic molecules, including pharmaceuticals, agrochemicals, and advanced materials. This compound is primarily sought by research and development chemists, process development scientists, and manufacturers in the fine chemical and pharmaceutical industries for use in Diels-Alder reactions and other cycloaddition processes.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug molecules and active pharmaceutical ingredients (APIs) via cycloaddition chemistry.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, leveraging its reactivity to construct heterocyclic cores.
• Material Science Research: Serves as a monomer or building block for the development of specialty polymers and advanced organic materials with tailored properties.
• Academic & Industrial R&D: A valuable reagent for methodological development in organic synthesis, particularly in studies involving pericyclic reactions.
• Flavor & Fragrance Industry: Potential intermediate for the synthesis of certain terpenoid and aromatic compounds used in fragrance creation.

Basic Information

Product Name	3-Methylene-1,4-Cyclohexadiene
CAS No.	3217-87-6
Molecular Formula	C7H8
Molecular Weight	92.14 g/mol
Synonyms	1,4-Cyclohexadiene, 3-methylene-; 3-Methylenecyclohexa-1,4-diene; 3-Methylene-1,4-cyclohexadiene; 1,3-Cyclohexadiene, 5-methylene-; 5-Methylene-1,3-cyclohexadiene; NSC 163075
EINECS	221-746-5

Quality Control

Our 3-Methylene-1,4-Cyclohexadiene is produced and handled under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including chromatographic purity analysis and identity confirmation, to ensure it meets the high standards required for research and industrial synthesis. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting key parameters such as assay and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry, and well-ventilated area. Recommended long-term storage temperature is 2-8°C. Due to its reactive nature, keep away from strong oxidizers and sources of ignition.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 95.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.