Description

4-Chloromercuribenzoic Acid Sodium Salt is a specialized organomercury compound primarily used as a selective reagent in biochemical and analytical chemistry. Its core value lies in its ability to react with sulfhydryl (-SH) groups, making it an essential tool for protein modification, enzyme inhibition studies, and the determination of thiol compounds. This high-purity reagent is critical for researchers and quality control laboratories in the pharmaceutical, biotechnology, and life science sectors who require precise and reliable chemical tools for their analytical workflows.

Application

• Biochemical Research: Used as a specific reagent for the modification and titration of cysteine residues in proteins and peptides.
• Enzyme Inhibition Studies: Acts as a potent inhibitor for thiol-dependent enzymes, aiding in the study of enzyme mechanisms and active sites.
• Analytical Chemistry: Employed in the quantitative determination of thiol groups (mercaptans) in various biological and chemical samples.
• Pharmaceutical Development: Utilized in the synthesis and quality control of drug candidates that contain or target sulfhydryl functionalities.
• Protein Structure Analysis: Aids in mapping protein structure and function by selectively blocking sulfhydryl sites.
• Reagent for Organic Synthesis: Serves as a specialized intermediate or catalyst in specific organometallic synthesis routes.

Basic Information

Product Name	4-Chloromercuribenzoic Acid Sodium Salt
CAS No.	3198-04-7
Molecular Formula	C7H4ClHgNaO2
Molecular Weight	379.14 g/mol
Synonyms	p-Chloromercuribenzoic Acid Sodium Salt; Sodium p-Chloromercuribenzoate; PCMB Sodium Salt; 4-(Chloromercuri)benzoic Acid Sodium Salt; (4-Carboxyphenyl)chloromercury Sodium Salt; Sodium (4-Carboxyphenyl)chloromercury; PCMB-Na; Sodium PCMB
EINECS	221-705-6

Quality Control

Our 4-Chloromercuribenzoic Acid Sodium Salt is manufactured under strict quality management protocols. Each batch undergoes rigorous analytical testing, including assay by titration and identification by FT-IR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing purity, heavy metal content, and other critical parameters is provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; containers must be kept tightly sealed after opening to minimize exposure to atmospheric moisture and light to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (Titration)	≥ 98.0 %
Loss on Drying	≤ 1.0 %
Heavy Metals (as Pb)	≤ 20 ppm
Mercury Content	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.