Description

7-Methoxy-Chroman-3-Carboxylic Acid is a specialized organic compound belonging to the chroman family, serving as a crucial chiral building block and intermediate in advanced organic synthesis. Its unique bicyclic structure with a methoxy substituent and carboxylic acid functionality makes it a valuable precursor for developing complex molecules with specific stereochemistry. This high-purity intermediate is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for the development of new active ingredients.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of novel therapeutic agents, particularly for central nervous system (CNS) and cardiovascular drugs.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides, where its chroman core contributes to biological activity.
• Fine Chemical Production: Serves as a versatile building block for synthesizing flavors, fragrances, and other high-value specialty chemicals.
• Academic & R&D: Employed in organic chemistry research for methodological studies and the construction of complex natural product analogs.
• Material Science Precursor: Potential use in synthesizing organic ligands and functional molecules for advanced materials.

Basic Information

Product Name	7-Methoxy-Chroman-3-Carboxylic Acid
CAS No.	3187-51-7
Molecular Formula	C11H12O4
Molecular Weight	208.21 g/mol
Synonyms	3-Chromancarboxylic acid, 7-methoxy-; 7-Methoxy-3,4-dihydro-2H-1-benzopyran-3-carboxylic acid; 7-Methoxychroman-3-carboxylic acid; 7-Methoxy-2,3-dihydro-4H-chromene-3-carboxylic acid; 7-Methoxy-3,4-dihydro-2H-chromene-3-carboxylic acid; 7-Methoxy-2,3-dihydro-1,4-benzoxazine-3-carboxylic acid (tautomeric form); 3187-51-7 (CAS).
EINECS	221-694-8

Quality Control

Our 7-Methoxy-Chroman-3-Carboxylic Acid is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. We provide comprehensive analytical documentation, including Certificates of Analysis (COA) detailing purity, identity, and impurity profiles via validated methods such as HPLC, GC, and NMR. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your critical synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed to exclude moisture. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Related Substances (HPLC)	Any individual impurity ≤ 0.5%; Total impurities ≤ 1.0%
Optical Rotation (if chiral)	Specific rotation provided per batch

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.