Description

(2R)-3,4-Dihydro-5,7-Dimethoxy-2α-(3,4,5-Trimethoxyphenyl)-2H-1-Benzopyran-3α-Ol CAS NO 3143-37-1 is a high-purity, synthetic chromane derivative of significant interest in advanced organic synthesis and pharmaceutical research. This compound serves as a critical chiral building block and intermediate for developing novel bioactive molecules. It is primarily needed by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the synthesis of complex natural product analogs and potential therapeutic agents.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new drug candidates, particularly in oncology and CNS therapeutic areas.
• Organic Synthesis Building Block: Used in asymmetric synthesis to construct complex chromane and flavanone-based molecular architectures.
• Reference Standard: Serves as a high-purity analytical standard for method development and quality control in pharmaceutical analysis.
• Biochemical Research: Employed in studies investigating enzyme inhibition and receptor-ligand interactions due to its specific stereochemistry.
• Material Science Precursor: Potential intermediate for synthesizing specialized polymers or ligands with specific optical properties.

Basic Information

Product Name	(2R)-3,4-Dihydro-5,7-Dimethoxy-2α-(3,4,5-Trimethoxyphenyl)-2H-1-Benzopyran-3α-Ol
CAS No.	3143-37-1
Molecular Formula	C20H24O7
Molecular Weight	376.40 g/mol
Synonyms	(2R)-5,7-Dimethoxy-2-(3,4,5-trimethoxyphenyl)chroman-3-ol; (2R)-2,3-Dihydro-5,7-dimethoxy-2-(3,4,5-trimethoxyphenyl)-4H-1-benzopyran-4-ol; NSC 407347; (2R)-3,4-Dihydro-5,7-dimethoxy-2-(3,4,5-trimethoxyphenyl)-2H-1-benzopyran-3-ol; (-)-3,4-Dihydro-5,7-dimethoxy-2-(3,4,5-trimethoxyphenyl)-2H-1-benzopyran-3-ol; (2R)-Flavan-3-ol derivative
EINECS	Contact for details

Quality Control

Our (2R)-3,4-Dihydro-5,7-Dimethoxy-2α-(3,4,5-Trimethoxyphenyl)-2H-1-Benzopyran-3α-Ol is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for research and synthesis. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided and available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is light-sensitive (store away from light). Keep the container tightly sealed in a dry environment to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.