Description

(2R)-3,4-Dihydro-5,7-Dimethoxy-2α-(4-Methoxyphenyl)-2H-1-Benzopyran-3α-Ol CAS NO 3143-21-3 is a high-purity chiral flavan derivative, a key intermediate in advanced organic synthesis. This compound is valued for its defined stereochemistry and structural complexity, which are critical for producing compounds with specific biological activity. It is primarily sought by research institutions and pharmaceutical development companies for use in medicinal chemistry, asymmetric synthesis, and as a building block for novel therapeutic agents.

Application

• Pharmaceutical Intermediate: Serves as a crucial chiral building block in the synthesis of potential drug candidates, particularly in central nervous system (CNS) and cardiovascular research.
• Medicinal Chemistry Research: Used as a scaffold or precursor for developing new chemical entities (NCEs) with targeted biological properties.
• Asymmetric Synthesis: Employed as a starting material or ligand precursor in catalytic asymmetric reactions due to its defined (2R) configuration.
• Flavonoid Analogue Synthesis: Acts as a key intermediate for the preparation of synthetic and semi-synthetic flavonoid derivatives for biological evaluation.
• Reference Standard: Used as an analytical standard in quality control and method development for related compounds in pharmaceutical and research settings.

Basic Information

Product Name	(2R)-3,4-Dihydro-5,7-Dimethoxy-2α-(4-Methoxyphenyl)-2H-1-Benzopyran-3α-Ol
CAS No.	3143-21-3
Molecular Formula	C19H22O5
Molecular Weight	330.38 g/mol
Synonyms	(2R)-5,7-Dimethoxy-2-(4-methoxyphenyl)chroman-3-ol; (2R)-3,4-Dihydro-5,7-dimethoxy-2-(4-methoxyphenyl)-2H-1-benzopyran-3-ol; (2R)-2-(4-Methoxyphenyl)-5,7-dimethoxychroman-3-ol; (2R)-Flavan-3-ol derivative; 2R-Flavan derivative; (2R)-trans-2-(4-Methoxyphenyl)-3-hydroxy-5,7-dimethoxychroman; (2R)-2-(p-Methoxyphenyl)-5,7-dimethoxychroman-3-ol
EINECS	Contact for details

Quality Control

Our (2R)-3,4-Dihydro-5,7-Dimethoxy-2α-(4-Methoxyphenyl)-2H-1-Benzopyran-3α-Ol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure high chemical and stereochemical purity suitable for research and development applications. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability and compliance with your project specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is light-sensitive (store away from light). For long-term storage, consider inert atmosphere conditions to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.