Description

3,5-Di-tert-Butyl-4-Hydroxybenzenepropanoyl Chloride is a versatile and highly reactive acyl chloride derivative of the hindered phenol antioxidant family. This compound serves as a crucial key intermediate for synthesizing advanced polymer additives and specialty chemicals, offering a reactive handle for introducing sterically hindered phenolic functionality into larger molecules. It is primarily needed by R&D chemists, polymer scientists, and manufacturers in the polymer, lubricant, and specialty chemical industries seeking to develop high-performance stabilizers and antioxidants.

Application

• Primary Intermediate for Antioxidants: Key building block for synthesizing high-molecular-weight, polymeric hindered phenol antioxidants (e.g., Irganox 1010 analogs) used in plastics and polymers.
• Polymer Stabilizer Synthesis: Used to create multifunctional stabilizers that protect polymers like polyolefins (PP, PE) from thermal and oxidative degradation during processing and end-use.
• Lubricant & Fuel Additive Precursor: Intermediate in the production of additives that prevent oxidation and sludge formation in engine oils, industrial lubricants, and fuels.
• Specialty Chemical Synthesis: Reactive site for attaching the hindered phenol moiety to other molecules, creating custom antioxidants, UV stabilizers, or bioactive compounds for pharmaceutical research.
• Rubber Industry: Used in the synthesis of antidegradants that protect synthetic and natural rubber from aging and flex-cracking.
• Adhesive & Coating Additives: Precursor for additives that enhance the thermal stability and longevity of adhesives, sealants, and protective coatings.

Basic Information

Product Name	3,5-Di-tert-Butyl-4-Hydroxybenzenepropanoyl Chloride
CAS No.	3062-64-4
Molecular Formula	C17H25ClO2
Molecular Weight	296.83 g/mol
Synonyms	3-(3,5-Di-tert-butyl-4-hydroxyphenyl)propionyl chloride; 3,5-Di-tert-butyl-4-hydroxyhydrocinnamoyl chloride; Propionic acid, 3-(3,5-bis(1,1-dimethylethyl)-4-hydroxyphenyl)-, chloride; Benzenepropanoyl chloride, 3,5-bis(1,1-dimethylethyl)-4-hydroxy-; Antioxidant 1010 intermediate; Phenolic acyl chloride; Hindered phenol chloride
EINECS	221-296-5

Quality Control

Our production of 3,5-Di-tert-Butyl-4-Hydroxybenzenepropanoyl Chloride adheres to stringent quality protocols to ensure batch-to-batch consistency and high reactivity. Every lot is analyzed using advanced techniques like HPLC and NMR to confirm identity and purity. Certificates of Analysis (COA) detailing purity, assay, and impurity profiles are provided with each shipment. We operate under a cGMP-compliant quality management system, and our facilities are prepared to meet the specific documentation requirements of pharmaceutical and advanced material supply chains.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, containers must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent hydrolysis and degradation. Keep away from heat, open flames, and incompatible materials such as strong bases, alcohols, and water.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	95 - 100 °C
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.