Description

cis-Octahydro-4A(2H)-Naphthalenecarboxylic Acid is a high-purity, saturated bicyclic carboxylic acid derivative, serving as a critical chiral building block and intermediate in advanced organic synthesis. Its rigid, fused ring structure and defined stereochemistry make it invaluable for constructing complex molecular architectures with precise spatial orientation. This compound is essential for research and development chemists in the pharmaceutical, agrochemical, and specialty chemical industries, particularly for applications requiring high stereochemical fidelity.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of active pharmaceutical ingredients (APIs), especially in the development of central nervous system (CNS) drugs and hormone analogs.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides, where its structural framework contributes to biological activity and selectivity.
• Ligand and Catalyst Development: Serves as a precursor for creating novel chiral ligands and organocatalysts used in asymmetric synthesis.
• Fragrance and Flavor Chemistry: Acts as an intermediate for synthesizing specific musky or amber odorants and complex flavor molecules.
• Material Science Research: Employed in the development of specialty polymers and liquid crystals, where its rigid core influences material properties.
• Academic and R&D Laboratories: A valuable reagent for methodological studies in organic chemistry, including cyclization and stereoselective reactions.

Basic Information

Product Name	cis-Octahydro-4A(2H)-Naphthalenecarboxylic Acid
CAS No.	3021-73-6
Molecular Formula	C11H18O2
Molecular Weight	182.26 g/mol
Synonyms	4a,5,6,7,8,8a-Hexahydro-4aH-naphthalene-2-carboxylic acid; cis-Perhydro-2-naphthoic acid; cis-Decahydro-2-naphthoic acid; (4aS,8aR)-Decahydronaphthalene-2-carboxylic acid; Bicyclo[4.4.0]decane-2-carboxylic acid; cis-Hexahydro-4a(2H)-naphthalenecarboxylic acid; 2-Naphthalenecarboxylic acid, octahydro-, cis-; cis-Octalin-2-carboxylic acid
EINECS	Contact for details

Quality Control

Every batch of cis-Octahydro-4A(2H)-Naphthalenecarboxylic Acid is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the product meets the high standards required for research and industrial synthesis. A Certificate of Analysis (COA) detailing purity, enantiomeric excess (where applicable), and impurity profiles is supplied with each shipment. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after each use to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants or storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 10 ppm
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.