Description

1,1,1,2,2-Pentafluoro-3-Methylbutan-3-Ol CAS NO 374-46-9 is a highly fluorinated tertiary alcohol, valued for its unique combination of volatility and chemical reactivity. This compound serves as a critical building block and intermediate in advanced chemical synthesis, particularly where the introduction of fluorine atoms is required to modify material properties. It is essential for R&D and production in the pharmaceutical, agrochemical, and specialty materials sectors seeking to enhance product performance through fluorination.

Application

• Pharmaceutical Intermediate: Used in the synthesis of novel active pharmaceutical ingredients (APIs), especially those requiring fluorinated motifs for improved metabolic stability and bioavailability.
• Agrochemical Synthesis: Acts as a key precursor for developing advanced herbicides, pesticides, and fungicides with enhanced efficacy and environmental profile.
• Fluorinated Polymer & Material Science: Serves as a monomer or modifier in the production of specialty polymers, coatings, and surfactants to impart oil/water repellency, chemical resistance, and low surface energy.
• Electronics & Semiconductor Industry: Employed in the formulation of specialty cleaning agents, etching solutions, and as a precursor for dielectric fluids.
• Organic Synthesis & Catalysis: Utilized as a versatile fluorinating agent or as a scaffold in complex molecule construction for academic and industrial research.
• Liquid Crystal & Display Technology: A potential component in the synthesis of fluorinated liquid crystals for high-performance displays.

Basic Information

Product Name	1,1,1,2,2-Pentafluoro-3-Methylbutan-3-Ol
CAS No.	374-46-9
Molecular Formula	C5H5F5O
Molecular Weight	176.09 g/mol
Synonyms	3-Methyl-3-(pentafluoroethyl)butan-3-ol; 3-Hydroxy-3-methyl-1,1,1,2,2-pentafluorobutane; Pentafluoroethyl Dimethyl Carbinol; Hexafluoro-tert-butanol (common misnomer, related compound); 1,1,1,2,2-Pentafluoro-3-methyl-3-butanol; 3-Methyl-3-pentafluoroethyl-3-ol; (Pentafluoroethyl)dimethylcarbinol
EINECS	206-779-9

Quality Control

Our 1,1,1,2,2-Pentafluoro-3-Methylbutan-3-Ol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including GC, HPLC, NMR, and Karl Fischer titration, to ensure high purity and consistent performance. Certificates of Analysis (COA) detailing identity, assay, and impurity profiles are provided with every shipment. We support compliance with relevant global regulatory frameworks.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Due to its highly volatile nature, ensure containers are kept tightly sealed when not in use. Keep away from strong acids, bases, and oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms
Assay (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (GC)	Individual impurity ≤ 1.0%
Total Impurities	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.