Description

3,3,4,4-Tetrafluorotetrahydrofuran is a versatile fluorinated heterocyclic compound that serves as a critical building block in advanced chemical synthesis. Its unique structure, featuring a fully fluorinated carbon backbone adjacent to an oxygen atom, makes it a valuable precursor for introducing fluorinated tetrahydrofuran motifs into target molecules. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty materials sectors who require high-purity fluorinated intermediates to develop new products with enhanced properties.

Application

• Pharmaceutical Intermediate: Key synthon for the development of fluorinated active pharmaceutical ingredients (APIs), potentially enhancing metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in creating novel fluorinated pesticides and herbicides, where fluorine atoms can improve efficacy and environmental profile.
• Liquid Crystal & Electronic Materials: Serves as a precursor for fluorinated components in liquid crystal displays (LCDs) and dielectric fluids.
• Polymer & Material Science: Building block for synthesizing fluorinated polymers and coatings, imparting properties like chemical resistance, low surface energy, and thermal stability.
• Organic Synthesis & Catalysis: Valuable reagent in organofluorine chemistry for constructing complex molecules; can be used to study ring-opening reactions and polymerization mechanisms.
• Solvent & Reaction Medium: Potential use as a specialty fluorinated solvent for demanding chemical processes.

Basic Information

Item	Detail
Product Name	3,3,4,4-Tetrafluorotetrahydrofuran
CAS No.	374-33-4
Molecular Formula	C4H4F4O
Molecular Weight	144.07 g/mol
Synonyms	Perfluorotetrahydrofuran; 2,2,3,3-Tetrafluorotetrahydrofuran; Tetrafluorotetrahydrofuran; 3,3,4,4-Tetrafluorooxolane; Furan, tetrahydro-3,3,4,4-tetrafluoro-; NSC 92436; 3,3,4,4-Tetrafluorotetrahydrofuran (contains BHT as inhibitor)
EINECS	206-786-7

Quality Control

Our 3,3,4,4-Tetrafluorotetrahydrofuran is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including GC, NMR, and Karl Fischer titration, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with agreed specifications. Our quality commitment supports your R&D and production needs with reliable, high-purity material.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, well-ventilated area away from heat sources and incompatible materials. Due to its properties as a strong acid/organic solvent and highly volatile nature, containers must be kept tightly sealed and under an inert atmosphere if specified. Recommended storage temperature is 2-8°C for extended stability, though short-term storage at controlled room temperature (15-25°C) is acceptable.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 98.0%
Water Content (KF)	≤ 0.1%
Density (20°C)	~1.45 g/mL
Boiling Point	~105-110°C
Refractive Index (n20/D)	~1.35

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.