Description

Octadecyl Trimethyl Ammonium Fluoride is a high-purity, long-chain quaternary ammonium fluoride salt, valued for its dual functionality as a phase-transfer catalyst and a source of nucleophilic fluoride ion. This compound is essential for facilitating challenging organic synthesis reactions in non-polar media, particularly fluorination and nucleophilic substitution processes. It is a critical reagent for R&D laboratories and production facilities in the pharmaceutical, agrochemical, and specialty chemical industries seeking efficient, anhydrous reaction pathways.

Application

• Phase-Transfer Catalyst (PTC): Enables reactions between reagents in immiscible liquid phases, significantly improving yield and reaction rate in alkylation and esterification processes.
• Nucleophilic Fluorination Agent: Provides a soluble source of fluoride ion (F⁻) for the synthesis of fluoroorganic compounds, fluorinated pharmaceuticals, and agrochemicals.
• Surface Modification: Used to impart hydrophobic and antimicrobial properties to textiles, polymers, and materials in industrial manufacturing.
• Analytical Chemistry: Serves as an ion-pairing agent in chromatography and as a reagent in specific fluoride-ion selective electrode methodologies.
• Catalyst in Polymerization: Acts as a catalyst or co-catalyst in the production of certain silicone polymers and other specialty resins.
• Research & Development: A key building block and reagent in organic synthesis for developing new chemical entities and novel fluorination methodologies.

Basic Information

Product Name	Octadecyl Trimethyl Ammonium Fluoride
CAS No.	373-43-3
Molecular Formula	C₂₁H₄₆FN
Molecular Weight	331.61 g/mol
Synonyms	Stearyltrimethylammonium Fluoride; Octadecyltrimethylazanium Fluoride; N,N,N-Trimethyl-1-octadecanaminium Fluoride; STAF; OTAF; C18-TMAF; 1-Octadecanaminium, N,N,N-trimethyl-, fluoride; Arquad 18-fluoride
EINECS	206-775-1

Quality Control

Every batch of Octadecyl Trimethyl Ammonium Fluoride is manufactured and tested under a strict quality management system. We provide comprehensive analytical documentation to ensure product integrity and traceability for your regulatory needs. A detailed Certificate of Analysis (COA) confirming identity, purity (Assay), and impurity profiles is supplied with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under a dry inert atmosphere (e.g., nitrogen or argon) to prevent decomposition. Keep away from strong acids and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder or solid
Identification (IR)	Conforms to structure
Assay (Titration)	≥ 98.0 %
Water Content (KF)	≤ 1.0 %
Heavy Metals (as Pb)	≤ 10 ppm
Residue on Ignition	≤ 0.1 %

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.