Description

α-Amino-3-Fluoro-4-Hydroxy-5-Iodobenzenepropionic Acid is a sophisticated halogenated aromatic amino acid derivative, serving as a critical building block in advanced organic synthesis. Its unique structure, featuring fluorine and iodine substituents on a phenolic ring, makes it a valuable precursor for creating novel compounds with targeted biological activity. This high-purity intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical sectors developing next-generation active ingredients.

Application

• Pharmaceutical Intermediate: Key synthon for the research and development of novel drug candidates, particularly in oncology and central nervous system (CNS) therapeutics.
• Agrochemical Synthesis: Used in the creation of advanced herbicides and pesticides, leveraging its halogenated structure for enhanced bioactivity.
• Biochemical Research: Serves as a specialized probe or substrate in enzymatic studies and metabolic pathway analysis.
• Peptide Modification: Incorporation into peptide chains to study structure-activity relationships (SAR) and improve metabolic stability.
• Ligand Development: Foundation for creating complex ligands used in catalysis and molecular recognition applications.
• Radiopharmaceutical Precursor: Potential use in developing diagnostic imaging agents due to the presence of the iodine atom.

Basic Information

Product Name	α-Amino-3-Fluoro-4-Hydroxy-5-Iodobenzenepropionic Acid
CAS No.	369-97-1
Molecular Formula	C9H9FINO3
Molecular Weight	325.08 g/mol
Synonyms	3-Fluoro-4-hydroxy-5-iodo-DL-phenylalanine; DL-3-Fluoro-4-hydroxy-5-iodophenylalanine; 2-Amino-3-(3-fluoro-4-hydroxy-5-iodophenyl)propanoic acid; (RS)-2-Amino-3-(3-fluoro-4-hydroxy-5-iodophenyl)propionic acid; 3-Fluoro-5-iodotyrosine; FIHPA; 369-97-1 (CAS Registry Number)
EINECS	Contact for details

Quality Control

Our α-Amino-3-Fluoro-4-Hydroxy-5-Iodobenzenepropionic Acid is manufactured under strict quality management systems. Each batch is subjected to comprehensive analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for research and commercial synthesis. Certificates of Analysis (COA) documenting all critical parameters are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.