Description

4-Fluoroacetanilide is a key fluorinated aromatic intermediate with significant synthetic utility. Its value lies in its role as a versatile building block for introducing the 4-fluoroaniline moiety into more complex molecules, enabling the development of advanced materials and active compounds. This product is essential for research and production in the pharmaceutical, agrochemical, and specialty chemical industries, where precise fluorination is critical for modifying biological activity and material properties.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of various active pharmaceutical ingredients (APIs), particularly those requiring a fluorinated aromatic ring system.
• Agrochemical Synthesis: Used in the manufacture of advanced herbicides, fungicides, and pesticides, where fluorine substitution enhances efficacy and environmental stability.
• Liquid Crystal & OLED Material Production: Serves as a starting material for fluorinated compounds used in electronic displays and organic light-emitting diodes.
• Dye & Pigment Manufacturing: Acts as an intermediate for creating specialized fluorinated dyes and pigments with unique color fastness and properties.
• Organic Synthesis & Research: A valuable reagent in academic and industrial R&D for constructing complex fluoroorganic molecules and exploring new chemical spaces.
• Polymer Modification: Employed to introduce fluorine-containing side chains into polymers, altering their surface energy, chemical resistance, and thermal stability.

Basic Information

Product Name	4-Fluoroacetanilide
CAS No.	351-83-7
Molecular Formula	C8H8FNO
Molecular Weight	153.15 g/mol
Synonyms	N-(4-Fluorophenyl)acetamide; p-Fluoroacetanilide; 4'-Fluoroacetanilide; 1-Acetamido-4-fluorobenzene; Acetamide, N-(4-fluorophenyl)-; 4-Fluoroacetamilide; 4-Fluoro-N-phenylacetamide; N-Acetyl-4-fluoroaniline
EINECS	206-517-8

Quality Control

Our 4-Fluoroacetanilide is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. We employ advanced analytical techniques, including HPLC, GC, and NMR, to verify identity and quantify impurities. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and specific impurity limits is provided with each shipment. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.5%
Melting Point	148°C - 152°C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Total impurities ≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.