Description

4'-Bromo-3'-Fluoroacetanilide is a high-purity halogenated aniline derivative, serving as a critical building block in advanced organic synthesis. Its value lies in providing a versatile, functionalized aromatic core for constructing complex molecules, particularly in pharmaceutical research and development. This intermediate is essential for medicinal chemists and process development scientists working on new active pharmaceutical ingredients (APIs) and agrochemicals, where the introduction of bromine and fluorine atoms is strategically important for modulating biological activity and physicochemical properties.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, especially those targeting central nervous system (CNS) disorders, anti-inflammatory agents, and oncology therapeutics.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and pesticides, where the halogen atoms contribute to efficacy and environmental stability.
• Liquid Crystal & OLED Material Research: Serves as a starting material for synthesizing functionalized aromatic compounds used in electronic displays and organic light-emitting diodes.
• Dye & Pigment Manufacturing: Acts as an intermediate for producing specialized azo dyes and high-performance pigments.
• Cross-Coupling Reactions: The bromine substituent makes it an excellent substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck, Sonogashira) to create complex biaryl structures.
• Academic & Contract Research: Employed in university and CRO laboratories for methodological development and exploring new synthetic pathways.

Basic Information

Product Name	4'-Bromo-3'-Fluoroacetanilide
CAS No.	351-30-4
Molecular Formula	C8H7BrFNO
Molecular Weight	232.05 g/mol
Synonyms	N-(4-Bromo-3-fluorophenyl)acetamide; 4-Bromo-3-fluoroacetanilide; 1-Acetamido-4-bromo-3-fluorobenzene; 4'-Bromo-3'-fluoroacetamilide; Acetamide, N-(4-bromo-3-fluorophenyl)-; 4-Bromo-3-fluoro-N-acetylaniline; N-Acetyl-4-bromo-3-fluoroaniline
EINECS	Contact for details

Quality Control

Our 4'-Bromo-3'-Fluoroacetanilide is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via FT-IR and NMR spectroscopy, to ensure it meets the high standards required for research and production. Certificates of Analysis (COA) with detailed chromatographic data are provided for full traceability and quality assurance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents, strong acids, and strong bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	142 - 147 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.