Description

5-Chloro-2-Trifluoro Methoxy Aniline is a versatile halogenated aniline derivative that serves as a critical building block in advanced organic synthesis. Its unique molecular structure, featuring both chloro and trifluoromethoxy substituents, makes it an essential intermediate for creating compounds with tailored electronic and steric properties. This high-purity intermediate is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for the development of active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for drugs targeting the central nervous system and anti-inflammatory applications.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides, where the trifluoromethoxy group enhances biological activity and environmental stability.
• Liquid Crystal & OLED Materials: Serves as a building block for electron-transport materials and charge-generating compounds in electronic displays and organic light-emitting diodes.
• Dye & Pigment Manufacturing: Acts as an intermediate for producing high-performance, light-fast azo dyes and complex pigments.
• Polymer Chemistry: Employed in the synthesis of specialty polymers and resins, where it can impart unique solubility and thermal properties.
• Research & Development: A valuable reagent in academic and industrial R&D for exploring new chemical entities and reaction pathways in medicinal and materials chemistry.

Basic Information

Product Name	5-Chloro-2-Trifluoro Methoxy Aniline
CAS No.	326-64-7
Molecular Formula	C7H5ClF3NO
Molecular Weight	211.57 g/mol
Synonyms	2-Amino-4-chloro-1-(trifluoromethoxy)benzene; 4-Chloro-2-(trifluoromethoxy)aniline; 5-Chloro-α,α,α-trifluoro-o-anisidine; 5-Chloro-2-(trifluoromethoxy)benzenamine; 5-Chloro-2-trifluoromethoxy-phenylamine; 2-Trifluoromethoxy-5-chloroaniline; Benzenamine, 4-chloro-2-(trifluoromethoxy)-
EINECS	Contact for details

Quality Control

Our 5-Chloro-2-Trifluoro Methoxy Aniline is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to confirm identity and purity while monitoring for specified impurities. A Certificate of Analysis (COA) detailing all test results is provided with every shipment. We support compliance with global regulatory frameworks, including REACH, and can supply material suitable for GMP applications upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.