Description

(R)-5-Benzyl-2-Phenyl-5,6-Dihydro-8H-[1,2,4]Triazolo[3,4-C][1,4]Oxazin-2-Ium Tetrafluoroborate is a high-purity, advanced pharmaceutical intermediate featuring a complex fused triazolo-oxazinium core structure. This compound is of significant value for its role as a key chiral building block in the research and development of novel active pharmaceutical ingredients (APIs). It is primarily needed by pharmaceutical R&D laboratories, process chemistry teams, and fine chemical manufacturers focused on creating new therapeutic agents, particularly in areas requiring sophisticated nitrogen-containing heterocycles.

Application

• Pharmaceutical Intermediate: Serves as a critical chiral precursor in the synthesis of potential new drug candidates, especially for central nervous system (CNS) or anti-infective targets.
• Asymmetric Synthesis: Utilized as a building block in asymmetric catalysis and synthesis due to its defined (R)-configuration and complex heterocyclic scaffold.
• Medicinal Chemistry Research: Employed in structure-activity relationship (SAR) studies and lead optimization programs to explore new chemical space.
• Process Development: Used for scaling up synthetic routes and developing robust, GMP-compliant manufacturing processes for clinical trial materials.
• Reference Standard: Acts as a high-purity analytical standard for method development and quality control in API production.
• Chemical Biology Probes: Potential use in developing molecular probes for studying biological pathways and target engagement.

Basic Information

Item	Details
Product Name	(R)-5-Benzyl-2-Phenyl-5,6-Dihydro-8H-[1,2,4]Triazolo[3,4-C][1,4]Oxazin-2-Ium Tetrafluoroborate
CAS No.	2828438-89-5
Molecular Formula	C22H20BF4N3O
Molecular Weight	429.22 g/mol
Synonyms	(R)-5-Benzyl-2-phenyl-5,6-dihydro-8H-[1,2,4]triazolo[3,4-c][1,4]oxazin-2-ium tetrafluoroborate; 5-Benzyl-2-phenyl-5,6-dihydro-8H-[1,2,4]triazolo[3,4-c][1,4]oxazin-2-ium tetrafluoroborate, (R)-; (R)-5-Benzyl-2-phenyl-5,6-dihydro-8H-[1,2,4]triazolo[3,4-c]oxazin-2-ium tetrafluoroborate; (R)-Triazolo-oxazinium Tetrafluoroborate Salt; (R)-enantiomer of 2828438-89-5; BPTOT; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Our (R)-5-Benzyl-2-Phenyl-5,6-Dihydro-8H-[1,2,4]Triazolo[3,4-C][1,4]Oxazin-2-Ium Tetrafluoroborate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure high chemical and enantiomeric purity suitable for advanced research applications. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under dry conditions to maintain stability. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.