Description

2-Oxabicyclo[2.1.1]Hexane-4-Carbonitrile, 1-(Hydroxymethyl)- is a high-value, functionalized bicyclic nitrile building block with significant synthetic utility. This compound is essential for advanced organic synthesis, particularly in the construction of complex molecular architectures for pharmaceutical and agrochemical research. It is primarily sought after by R&D chemists and process development scientists in the fine chemical, pharmaceutical, and advanced material sectors.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of novel active pharmaceutical ingredients (APIs), especially in nucleoside and carbocyclic analog development.
• Agrochemical Research: Used as a precursor for creating new herbicides, fungicides, and insecticides with unique modes of action.
• Ligand and Catalyst Development: Serves as a scaffold for designing novel chiral ligands and organocatalysts for asymmetric synthesis.
• Material Science: A potential monomer or cross-linking agent for specialty polymers with tailored thermal and mechanical properties.
• Chemical Biology Probe Synthesis: Employed in the creation of molecular probes for studying enzyme mechanisms and biological pathways.
• Academic & Industrial R&D: A versatile building block for methodological development in organic chemistry and medicinal chemistry programs.

Basic Information

Product Name	2-Oxabicyclo[2.1.1]Hexane-4-Carbonitrile, 1-(Hydroxymethyl)-
CAS No.	2757731-75-0
Molecular Formula	C7H9NO2
Molecular Weight	139.15 g/mol
Synonyms	1-(Hydroxymethyl)-2-oxabicyclo[2.1.1]hexane-4-carbonitrile; 2-Oxabicyclo[2.1.1]hexane-4-carbonitrile, 1-(hydroxymethyl)-; 1-(Hydroxymethyl)-2-oxabicyclo[2.1.1]hexane-4-carbonitrile; Bicyclo[2.1.1]hexane-4-carbonitrile, 1-(hydroxymethyl)-2-oxa-; (1R,4S)-1-(Hydroxymethyl)-2-oxabicyclo[2.1.1]hexane-4-carbonitrile (for specific enantiomer); OBN Building Block
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Each batch is characterized using advanced analytical techniques to guarantee identity, purity, and consistency. Certificates of Analysis (COA) detailing specific results for purity, chiral purity (if applicable), and impurity profiles are available upon request. We adhere to cGMP principles for the manufacture of advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to prevent moisture absorption. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.