Description

[(4R)-4,5-Dihydro-4-(1-Methylethyl)-2-Oxazolyl]-Ferrocene is a chiral, organometallic compound featuring a ferrocene core modified with a substituted oxazoline ligand. This unique structure makes it a highly valuable ligand precursor and chiral building block for asymmetric synthesis and catalysis. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries to develop novel synthetic pathways and enhance stereoselectivity.

Application

• Asymmetric Catalysis: Serves as a precursor for chiral ligands in transition metal-catalyzed reactions, including hydrogenation, cross-coupling, and cycloaddition.
• Pharmaceutical Intermediate: Used in the research and development of active pharmaceutical ingredients (APIs) requiring high enantiomeric purity.
• Agrochemical Synthesis: Employed as a chiral synthon in the production of advanced, stereospecific pesticides and herbicides.
• Material Science Research: Investigated for the development of novel organometallic complexes with unique electronic or magnetic properties.
• Academic & Industrial R&D: A key reagent for methodological studies in organic and organometallic chemistry for discovering new catalytic systems.

Basic Information

Product Name	[(4R)-4,5-Dihydro-4-(1-Methylethyl)-2-Oxazolyl]-Ferrocene
CAS No.	2757082-13-4
Molecular Formula	C16H19FeNO
Molecular Weight	297.18 g/mol
Synonyms	(R)-4-Isopropyl-2-ferrocenyl-4,5-dihydrooxazole; (R)-4-Isopropyl-2-ferrocenyl-2-oxazoline; Ferrocenyloxazoline Ligand Precursor; (R)-Fc-iPrOX; (4R)-4-(1-Methylethyl)-2-ferrocenyl-4,5-dihydrooxazole; (R)-2-Ferrocenyl-4-isopropyl-4,5-dihydrooxazole
EINECS	Contact for details

Quality Control

Our production of [(4R)-4,5-Dihydro-4-(1-Methylethyl)-2-Oxazolyl]-Ferrocene adheres to stringent internal quality standards to ensure batch-to-batch consistency and high enantiomeric purity. Each lot is characterized using advanced analytical techniques, including HPLC, NMR, and chiral analysis. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and chiral excess is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	Orange to red-brown crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Melting Point	Contact for details
Loss on Drying	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.