Description

Hydrazine, [(2,6-Difluorophenyl)Methyl]-, Hydrochloride (1:1) is a specialized organofluorine hydrazine derivative, serving as a high-value building block in advanced chemical synthesis. This compound matters for its role as a key precursor in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals, where its unique difluorophenylmethyl-hydrazine structure enables precise molecular modifications. It is primarily needed by research and development chemists, process development scientists, and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries seeking to incorporate this specific fluorinated motif into their target molecules.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting central nervous system (CNS) disorders, anti-infectives, and oncology.
• Agrochemical Synthesis: Used as a precursor in the development of next-generation herbicides, fungicides, and insecticides, leveraging the biological activity of the difluorophenyl group.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in asymmetric catalysis and transition metal complexes.
• Chemical Biology Research: Employed in the design and synthesis of molecular probes, enzyme inhibitors, and other tools for biochemical and pharmacological studies.
• Material Science Precursor: Potential use in the synthesis of monomers or additives for advanced polymeric materials with specific thermal or chemical resistance properties.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring this specific fluorinated hydrazine scaffold.

Basic Information

Product Name	Hydrazine, [(2,6-Difluorophenyl)Methyl]-, Hydrochloride (1:1)
CAS No.	2682115-59-7
Molecular Formula	C7H8ClF2N2
Molecular Weight	194.60 g/mol
Synonyms	1-[(2,6-Difluorophenyl)methyl]hydrazine hydrochloride; (2,6-Difluorobenzyl)hydrazine hydrochloride; N1-[(2,6-Difluorophenyl)methyl]hydrazine monohydrochloride; 2,6-Difluoro-α-hydrazinotoluene hydrochloride; [(2,6-Difluorophenyl)methyl]hydrazinium chloride; Hydrazine, [(2,6-difluorophenyl)methyl]-, monohydrochloride; 2,6-Difluorobenzylhydrazine HCl
EINECS	Contact for details

Quality Control

Our Hydrazine, [(2,6-Difluorophenyl)Methyl]-, Hydrochloride (1:1) is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all test results are provided with every shipment. We support development and commercial projects with material suitable for use under cGMP guidelines, as required.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and easily oxidized; containers should be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to maintain stability and purity. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.