Description

1H-Isoindole-1,3(2H)-Dione, 2-[(7-Bromo-3,4-Dihydro-4-Oxo-1-Phthalazinyl)Methyl]- is a high-purity, advanced pharmaceutical intermediate characterized by its complex heterocyclic structure incorporating isoindole and phthalazine moieties. This compound is of significant value for its role as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring targeted molecular scaffolds. It is primarily sought after by research institutions and pharmaceutical companies engaged in the development of new drug candidates, especially within oncology and central nervous system (CNS) research.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the multi-step synthesis of complex drug molecules and investigational new drugs.
• Oncology Research: Used in the development of potential anticancer agents, leveraging its brominated phthalazinyl structure for targeted activity.
• CNS Drug Discovery: Employed in medicinal chemistry programs aimed at creating novel compounds for neurological and psychiatric disorders.
• Chemical Biology: Functions as a specialized scaffold or probe in studying protein-ligand interactions and enzyme inhibition.
• Process Chemistry: Utilized in route scouting and optimization for the scalable production of high-value target molecules.
• Academic Research: Provides a versatile starting material for synthetic organic chemistry studies and the exploration of new heterocyclic reactions.

Basic Information

Product Name	1H-Isoindole-1,3(2H)-Dione, 2-[(7-Bromo-3,4-Dihydro-4-Oxo-1-Phthalazinyl)Methyl]-
CAS No.	2629316-05-6
Molecular Formula	C₁₇H₁₀BrN₃O₃
Molecular Weight	384.19 g/mol
Synonyms	2-[(7-Bromo-4-oxo-3,4-dihydrophthalazin-1-yl)methyl]isoindoline-1,3-dione; 7-Bromo-1-[(1,3-dioxoisoindolin-2-yl)methyl]phthalazin-4(1H)-one; N-(7-Bromo-4-oxo-3,4-dihydro-1-phthalazinylmethyl)phthalimide; Bromo-phthalazinyl-methyl phthalimide; Advanced Phthalazine-Isoindole Intermediate; API Intermediate 2629316-05-6
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality management systems, ensuring batch-to-batch consistency and high purity suitable for research and development applications. Quality is verified through comprehensive analytical techniques including HPLC, NMR, and mass spectrometry. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting identity, purity, and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). The compound may be light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity	≤ 0.5%
Total Impurities	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.