Description

Methanesulfonic Acid, 1,1,1-Trifluoro-, 8-Ethyl-7-Fluoro-3-(Methoxymethoxy)-1-Naphthalenyl Ester CAS NO 2621932-47-4 is a specialized fluorinated methanesulfonate ester derivative, designed for advanced synthetic applications. This high-purity intermediate is critical for researchers and manufacturers requiring precise molecular building blocks with unique reactivity profiles. It is primarily utilized in the development of novel active pharmaceutical ingredients (APIs), agrochemicals, and advanced materials where its specific fluorinated naphthalene structure imparts valuable properties.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of complex drug candidates, particularly in fluorinated quinolone or naphthyridine antibiotic research.
• Agrochemical Synthesis: Used in the development of next-generation herbicides and fungicides, leveraging the fluorinated moiety for enhanced biological activity and environmental stability.
• Material Science Research: Serves as a precursor for functionalized organic materials, including liquid crystals and polymers with tailored electronic properties.
• Cross-Coupling Reactions: Acts as an activated ester in palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Stille) for constructing complex biaryl systems.
• Fluorine Chemistry Studies: An important reagent for investigating the effects of trifluoromethanesulfonate groups on reaction kinetics and product stability in organic synthesis.
• Protecting Group Chemistry: The methoxymethoxy (MOM) group can serve as a protecting group for phenols or alcohols in multi-step synthetic sequences.

Basic Information

Product Name	Methanesulfonic Acid, 1,1,1-Trifluoro-, 8-Ethyl-7-Fluoro-3-(Methoxymethoxy)-1-Naphthalenyl Ester
CAS No.	2621932-47-4
Molecular Formula	C15H14F4O5S
Molecular Weight	382.33 g/mol
Synonyms	8-Ethyl-7-fluoro-3-(methoxymethoxy)-1-naphthyl trifluoromethanesulfonate; 1-Naphthalenol, 8-ethyl-7-fluoro-3-(methoxymethoxy)-, 1,1,1-trifluoromethanesulfonate; Trifluoromethanesulfonic acid 8-ethyl-7-fluoro-3-(methoxymethoxy)-1-naphthalenyl ester; 8-Ethyl-7-fluoro-3-MOM-1-naphthyl triflate; Fluorinated Naphthyl Triflate Ester; MOM-Protected Naphthyl Triflate; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Every batch of this advanced chemical intermediate is produced and analyzed under strict quality management protocols. We guarantee high purity and lot-to-lot consistency through comprehensive analytical techniques including HPLC, GC, NMR, and mass spectrometry. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting identity, purity, and impurity profiles to support your regulatory and R&D requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, containers should be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline solid or powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5% w/w
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.