Description

(2,2-Difluorocyclopropyl)-Trifluoro-Boranuide is a high-value organoboron reagent, specifically a trifluoroborate salt, designed for advanced cross-coupling reactions. This compound matters because it offers superior stability and handling compared to traditional boronic acids, enabling more efficient and reliable synthesis of complex fluorinated molecules. It is essential for R&D chemists and process development teams in the pharmaceutical and agrochemical industries who are developing novel active ingredients.

Application

• Pharmaceutical Intermediate Synthesis: A key building block in Suzuki-Miyaura cross-couplings for constructing fluorinated drug candidates, including protease inhibitors and kinase inhibitors.
• Agrochemical Research: Used to introduce the difluorocyclopropyl moiety into novel herbicides and fungicides, enhancing their metabolic stability and bioavailability.
• Material Science: Enables the synthesis of fluorinated monomers and polymers for specialty coatings, electronics, and advanced materials with unique surface properties.
• Catalyst & Ligand Development: Serves as a precursor for creating novel boron-containing ligands used in asymmetric catalysis.
• Fluorine Chemistry Libraries: A critical reagent for constructing diverse fluorinated compound libraries for high-throughput screening in drug discovery.

Basic Information

Product Name	(2,2-Difluorocyclopropyl)-Trifluoro-Boranuide
CAS No.	2416056-30-7
Molecular Formula	C5H5BF5
Molecular Weight	161.90 g/mol
Synonyms	Potassium (2,2-Difluorocyclopropyl)trifluoroborate; (2,2-Difluorocyclopropyl)trifluoroborate Potassium Salt; (2,2-Difluorocyclopropyl)trifluoroboranuide Potassium; Potassium (2,2-Difluorocyclopropyl)trifluoroboranuide; (2,2-Difluorocyclopropyl)BF3K; (2,2-Difluorocyclopropyl)Trifluoroboronate Potassium; Difluorocyclopropyl Trifluoroborate Potassium Salt
EINECS	Contact for details

Quality Control

Our (2,2-Difluorocyclopropyl)-Trifluoro-Boranuide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including NMR (1H, 11B, 19F) and HPLC analysis, to ensure high chemical purity and identity. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all specifications and test results to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C under an inert atmosphere (e.g., argon or nitrogen) due to its hygroscopic nature. Allow the container to reach room temperature before opening to minimize moisture ingress.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥95%
Potassium Content (ICP-OES)	22.0 - 25.0 %
Water Content (KF)	≤1.0 %

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.