Description

1-Bicyclo[1.1.1]Pentanyl(Trifluoro)Boranuide is a specialized organoboron reagent featuring a unique [1.1.1]propellane-derived cage structure. This compound matters as a highly valuable synthon in advanced organic synthesis, enabling the efficient introduction of the strained bicyclo[1.1.1]pentyl (BCP) moiety, a key pharmacophore in modern medicinal chemistry. Pharmaceutical researchers and agrochemical developers need it for creating novel bioactive molecules with improved metabolic stability and three-dimensional complexity.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing active pharmaceutical ingredients (APIs) targeting central nervous system (CNS) disorders and other therapeutic areas.
• Medicinal Chemistry: Used in fragment-based drug discovery and lead optimization to incorporate the BCP bioisostere, enhancing drug-like properties.
• Agrochemical Research: Employed in the development of new-generation herbicides and pesticides with novel modes of action.
• Materials Science: Precursor for advanced polymeric materials and liquid crystals, leveraging its rigid, three-dimensional geometry.
• Cross-Coupling Reactions: Acts as an organometallic reagent in Suzuki-Miyaura and other transition metal-catalyzed cross-coupling reactions.
• Academic & Industrial R&D: Fundamental reagent for methodological development in organic synthesis and catalysis studies.

Basic Information

Product Name	1-Bicyclo[1.1.1]Pentanyl(Trifluoro)Boranuide
CAS No.	2410559-72-5
Molecular Formula	C7H7BF3K
Molecular Weight	197.04 g/mol
Synonyms	Potassium 1-Bicyclo[1.1.1]pentyltrifluoroborate; Bicyclo[1.1.1]pentane-1-trifluoroborate Potassium Salt; BCP-BF3K; 1-(Trifluoroboranyl)bicyclo[1.1.1]pentane Potassium Salt; Potassium Bicyclo[1.1.1]pentyl-1-trifluoroboranuide; Potassium (Bicyclo[1.1.1]pent-1-yl)trifluoroborate; [1.1.1]Propellane-derived Trifluoroborate Salt
EINECS	Contact for details

Quality Control

Our 1-Bicyclo[1.1.1]Pentanyl(Trifluoro)Boranuide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including NMR (1H, 13C, 19F, 11B) and HPLC analysis, to ensure high chemical purity and identity. Certificates of Analysis (COA) with full analytical data are provided to guarantee compliance with research and development standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C under an inert atmosphere (e.g., argon or nitrogen) due to its hygroscopic and moisture-sensitive nature. Keep away from strong acids and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.